151590-36-2 Usage
General Description
"(E)-3-(6-methyl-1H-indol-3-yl)acrylic acid" is a chemical compound with the systematic name 3-(6-methyl-1H-indol-3-yl)prop-2-enoic acid. It is a derivative of the amino acid tryptophan, containing an indole group and a carboxylic acid functional group. (E)-3-(6-methyl-1H-indol-3-yl)acrylic acid has potential applications in the pharmaceutical and medicinal fields, as indole derivatives are known to exhibit various biological activities, including anticancer, antimicrobial, and anti-inflammatory properties. Additionally, the acrylic acid moiety in the molecule provides opportunities for further chemical modification to optimize its therapeutic properties. Study and research on the compound may contribute to the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 151590-36-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,5,9 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 151590-36:
(8*1)+(7*5)+(6*1)+(5*5)+(4*9)+(3*0)+(2*3)+(1*6)=122
122 % 10 = 2
So 151590-36-2 is a valid CAS Registry Number.
151590-36-2Relevant articles and documents
Discovery of a novel series of indolyl hydrazide derivatives as diacylglycerol acyltransferase-1 inhibitors
Kim, Minkyoung,Kwon, Jinsun,Kim, Mun Ock,Singh, Sarbjit,Kim, Sang Kyum,Lee, Kyeong,Lee, Kiho,Lee, Hyun Sun,Choi, Yongseok
, p. 628 - 635 (2015/05/04)
A novel series of hydrazide derivatives were synthesized as potential diacylglycerol acyltransferase (DGAT) inhibitors. Among them, compounds 8u and 8v exhibited selective and potent DGAT-1 inhibitory activities. In addition, compound 8u dose-dependently inhibited triglyceride synthesis in HepG2 cell lines. Furthermore, treatment with compound 8u for an oral lipid tolerance test showed a significant decrease in plasma triglyceride levels compared with vehicle-treated control animals, indicating delayed absorption of triglyceride after an acute lipid challenge.