1516-27-4

Basic information

• Product Name: allyltrimethylammonium chloride
• Synonyms: allyltrimethylammonium chloride;Allyltrimethylaminium·chloride;TriMethyl Allyl aMMoniuM chloride
• CAS NO: 1516-27-4
• Molecular Formula: C₆H₁₄N*Cl
• Molecular Weight: 135.63506
• EINECS: 216-164-3
• Product Categories: organic chemical
• Mol File: 1516-27-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 185-186 °C(Solv: acetone (67-64-1))
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: allyltrimethylammonium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: allyltrimethylammonium chloride(1516-27-4)
• EPA Substance Registry System: allyltrimethylammonium chloride(1516-27-4)

Safety Data

• Hazardous Substances Data: 1516-27-4(Hazardous Substances Data)

Usage

General Description

Allyltrimethylammonium chloride is a quaternary ammonium compound with the chemical formula C6H15NCl. It is a water-soluble, colorless liquid with a strong, ammoniacal odor. This chemical is primarily used in the production of cationic polymers, which are widely used in water treatment, papermaking, and the textile industry. It is also used as a surfactant, antistatic agent, and disinfectant. Allyltrimethylammonium chloride is considered to be toxic, and exposure can cause irritation to the skin, eyes, and respiratory system. It is important to handle and store this chemical with caution and in accordance with safety regulations.

InChI:InChI=1/C6H14N.ClH/c1-5-6-7(2,3)4;/h5H,1,6H2,2-4H3;1H/q+1;/p-1

Upstream product

• 593-81-7 trimethylamine hydrochloride 
• 106-95-6 allyl bromide 
• 107-05-1 3-chloroprop-1-ene 
• 75-50-3 trimethylamine 
• 95467-54-2 trimethyl-(3-chloro-propyl)-ammonium 

Downstream Products

• 7758-31-8 betaine aldehyde chloride 
• 187737-37-7 propene 
• 34557-54-5 methane 
• 75-50-3 trimethylamine 
• 124-40-3 dimethyl amine 

Relevant articles and documents

Synthetic approach for unsaturated precursors for parahydrogen induced polarization of choline and its analogs

Reported here are (i) a new synthetic approach for preparation of (ii) a new compound class, of -OH, for example, an -OH group is replaced with acetyl protecting group, protected 1,2-dehydrocholine analogs and (iii) a new synthetic route for betaine aldehyde. The C=C bond of 1,2-dehydrocholine moiety can be used for molecular addition of parahydrogen producing -OH protected hyperpolarized choline by parahydrogen-induced polarization (PHIP). The reported synthetic approach allows for incorporation of 15N and deuterium labels, which are necessary for preparation of highly polarized PHIP contrast agents. Isotope labeling with 15N and/or deuterium was conducted. Hyperpolarized 15N-choline enabled by the reported synthetic approach can be potentially used as an imaging biomarker of cancer similar to choline positron emission tomography tracers. Copyright

Site-Selective Installation of N?-Modified Sidechains into Peptide and Protein Scaffolds via Visible-Light-Mediated Desulfurative C–C Bond Formation

Post-translational modifications (PTMs) enhance the repertoire of protein function and mediate or influence the activity of many cellular processes. The preparation of site-specifically and homogeneously modified proteins, to apply as tools to understand the biological role of PTMs, is a challenging task. Herein, we describe a visible-light-mediated desulfurative C(sp3)–C(sp3) bond forming reaction that enables the site-selective installation of N?-modified sidechains into peptides and proteins of interest. Rapid, operationally simple, and tolerant to ambient atmosphere, we demonstrate the installation of a range of lysine (Lys) PTMs into model peptide systems and showcase the potential of this technology by site-selectively installing an N?Ac sidechain into recombinantly expressed ubiquitin (Ub).