151603-30-4

Upstream product

• 7719-09-7 thionyl chloride 
• 22433-91-6 2-bromoisophthalic acid 
• 576-22-7 2-Bromo-m-xylene 

Downstream Products

• 1026263-75-1 3-[3-(2,2-Bis-methoxycarbonyl-acetyl)-2-bromo-phenyl]-2-methoxycarbonyl-3-oxo-propionic acid methyl ester 
• 189632-07-3 2-Bromo-N,N'-bis-((S)-1-hydroxymethyl-2-phenyl-ethyl)-isophthalamide 
• 1276021-20-5 (+/-)-N,N'-bis(2-carbamoyl-3-methylbut-2-yl)-2-bromobenzene-1,3-dicarboxamide 
• 1276021-21-6 (+/-)-2-bromo-1,3-bis(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)benzene 
• 1276021-35-2 (S,S)-2-bromo-1,3-bis(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)benzene 
• 1276021-34-1 (S,S)-N,N'-bis(2-carbamoyl-3-methylbut-2-yl)-2-bromobenzene-1,3-dicarboxamide 
• 174833-49-9 2-bromo-1,3-diacetylbenzene 
• 1292781-17-9 2,6-bis(2-methyloxazol-4-yl)bromobenzene 
• 1292781-18-0 2-(2-methylthiazole-4-yl)-6-(2-methyloxazole-4-yl)bromobenzene 
• 1292781-21-5 C₁₂H₉Br₂NO₂ 
• 1448813-58-8 (2-bromo-1,3-phenylene)bis((diphenylphosphino)methanone) 
• 1448813-69-1 [NiBr{2,6-{Ph₂PC(O)}2(C₆H₃)}] 
• 189632-09-5 bromo-2,6-bis(4'-(S)-benzyloxazolin-2-yl)benzene 
• 189632-48-2 (S,S)-2,6-bis(4'-tert-butyl-2'-oxazolinyl)phenyl bromide 

Relevant academic research and scientific papers

A Masked Phosphinidene Trapped in a Fluxional NCN Pincer

The trapping of a phosphinidene (R-P) in an NCN pincer is presented. Stabilized phosphinidene 1 was characterized by31P{1H},1H, and13C{1H} NMR spectroscopy, exhibiting an averaged C2vsymmet

Electrochemical Generation of Hypervalent Bromine(III) Compounds

In sharp contrast to hypervalent iodine(III) compounds, the isoelectronic bromine(III) counterparts have been little studied to date. This knowledge gap is mainly attributed to the difficult-to-control reactivity of λ3-bromanes as well as to their challenging preparation from the highly toxic and corrosive BrF3 precursor. In this context, we present a straightforward and scalable approach to chelation-stabilized λ3-bromanes by anodic oxidation of parent aryl bromides possessing two coordinating hexafluoro-2-hydroxypropanyl substituents. A series of para-substituted λ3-bromanes with remarkably high redox potentials spanning a range from 1.86 V to 2.60 V vs. Ag/AgNO3 was synthesized by the electrochemical method. We demonstrate that the intrinsic reactivity of the bench-stable bromine(III) species can be unlocked by addition of a Lewis or a Br?nsted acid. The synthetic utility of the λ3-bromane activation is exemplified by oxidative C?C, C?N, and C?O bond forming reactions.

Catalytic Activation of N2O at a Low-Valent Bismuth Redox Platform

Herein we present the catalytic activation of N2O at a BiI→BiIII redox platform. The activation of such a kinetically inert molecule was achieved by the use of bismuthinidene catalysts, aided by HBpin as reducing agent. The protocol features remarkably mild conditions (25 °C, 1 bar N2O), together with high turnover numbers (TON, up to 6700) and turnover frequencies (TOF). Analysis of the elementary steps enabled structural characterization of catalytically relevant intermediates after O-insertion, namely a rare arylbismuth oxo dimer and a unique monomeric arylbismuth hydroxide. This protocol represents a distinctive example of a main-group redox cycling for the catalytic activation of N2O.

DERIVATIVES OF 7-FATTY ACID SUBSTITUTED BENZOXABOROLE AND THEIR PREPARATION AND USE

The present disclosure relates to derivatives of 7-fatty acid substituted benzoxaborole and their preparation and use. The structural general formula of the derivatives is (I). The derivatives are used for the preparation of a medicament for the preventio

Novel bisamide palladium(II) pincer complexes: effective catalysts in α-arylation of ketones

Three benzenedicarboxamide ligands (L) were designed and synthesized, and each was used to prepare a palladium(II) complex Pd(L)Br and Pd(L)(OAc). These NCN pincer complexes were used to catalyze the α-arylations of a variety of ketones with aryl chlorides or bromides in various solvents, and moderate-to-excellent yields were obtained (up to 95%). Further research showed that unactivated and sterically hindered aryl halides and ketones are also suitable substrates for the synthesis of α-arylation. Graphical Abstract: [Figure not available: see fulltext.].

Enantioselective hydrophosphination of enones with diphenylphosphine catalyzed by bis(imidazoline) NCN pincer palladium(II) complexes

A series of chiral NCN pincer Pd(II) complexes with 1,3-bis(2′- imidazolinyl)phenyl (Phebim) ligands were synthesized via the C-H activation or oxidative addition method. A dinuclear macrocyclic Pd(II) complex was also prepared by reaction of the Phebim-H

Novel bis(azole) pincer palladium complexes: Synthesis, structures and applications in Mizoroki-Heck reactions

Two novel NCN-pincer complex precursors bearing frameworks of 2,6-bis(oxazol-4-yl)benzene (A) and 2-(thiazol-4-yl)-6-(oxazol-4-yl)benzene (B) were synthesized. Palladations of A and B afforded two new bis(azole) pincer complexes, [(A-κ3NCN)PdBr] (1) and [(B-κ3NCN) PdBr] (2). Both complexes were fully characterized by NMR, MS, DSC-TGA and single-crystal X-ray diffraction analysis. Complex 1 crystallizes in a noncentrosymmetric orthorhombic space group Cmc21 (No. 36, Z = 4). Complex 2 crystallizes in a centrosymmetric monoclinic space group P2 1/n (No. 14, Z = 4). Despite the similarity in their chemical formulas, the structures of the two complexes are subtly different: they are built up of two-dimensional supramolecular layers with identical topology, but stacked in different sequences, i.e., the layers in complex 1 are stacked in an AAAA-type fashion, while those in complex 2 are stacked in an alternating AA-1AA-1 sequence (A denotes a layer; A-1 stands for A's inversion symmetry equivalent). In addition, the complexes showed good catalytic activity toward Mizoroki-Heck reactions. The Royal Society of Chemistry 2011.