151646-65-0Relevant academic research and scientific papers
Antioxidant properties of novel lipophilic ascorbic acid analogues
Weber, Valerie,Coudert, Pascal,Rubat, Catherine,Duroux, Eliane,Leal, Fernand,Couquelet, Jacques
, p. 523 - 530 (2007/10/03)
Structural modifications of ascorbic acid by the introduction of lipophilic moieties has led to derivatives with increased stability against thermal and oxidative degradation. Two series of new lipophilic ascorbic analogues were synthesized to obtain anti
Substituted γ-Lactones . Some Observations on the Synthesis and Reactivity of 4-Aroyl-3-hydroxy-2(5H)-furanones
Zimmer, Hans,Palmer-Sungail, R.,Ho, Douglas,Amer, Adel
, p. 161 - 167 (2007/10/02)
The reaction pathway towards formation of 4-aroyl-3-hydroxy-2(5H)-furanones 1 from the base catalysed reaction between an acetophenone, diethyl oxalate and formaldehyde was investigated.If methoxide was used as base, a transesterification was found to occur in the first step, while a side reaction, namely the retro Claisen reaction, was in competition with the desired lactone formation in the second step.The nature of the solvent and the acidic character of 1 as well as the basicity of the aminoarylene were found to have a product influence on the course of the reaction of 1 with aminoarylenes.
