151670-57-4Relevant academic research and scientific papers
A new route to enantiomerically pure 4,4-disubstituted cyclohex-2-en-1-ones: Asymmetric synthesis of (+)-mesembrine
Kosugi,Miura,Kanna,Uda
, p. 1409 - 1412 (2007/10/02)
Enantiomerically pure β,β-disubstituted vinyl sulfoxides undergo cycloaddition with dichloroketene to give β,β-disubstituted γ-lactones which are transformed into synthetically important 4,4-disubstituted cyclohex-2-enones in optically pure form. The present method is applied to the synthesis of enantiomerically pure (+)-mesembrine.
