151671-10-2 Usage
Uses
Used in Pharmaceutical Industry:
Tetraethyl(3-hydroxypropylidene)bisphosphonate is used as a therapeutic agent for the treatment of bone disorders such as osteoporosis and Paget's disease. It is utilized for its bone-protecting properties, which help to increase bone density and strength, thereby reducing the risk of fractures and other complications associated with these conditions.
Used in Oncology:
In the field of oncology, Tetraethyl(3-hydroxypropylidene)bisphosphonate is used for the treatment of certain types of cancers that have metastasized to the bone. Its application aids in reducing bone pain and preventing fractures caused by the cancerous invasion of bone tissue, thus improving the quality of life for cancer patients.
Used in Drug Development:
Tetraethyl(3-hydroxypropylidene)bisphosphonate is also used in the development of new pharmaceuticals targeting bone-related conditions. Its unique properties make it a valuable component in the creation of innovative treatments that can address a range of bone health issues more effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 151671-10-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,6,7 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 151671-10:
(8*1)+(7*5)+(6*1)+(5*6)+(4*7)+(3*1)+(2*1)+(1*0)=112
112 % 10 = 2
So 151671-10-2 is a valid CAS Registry Number.
151671-10-2Relevant academic research and scientific papers
PHOSPHONATE CONJUGATES AND USES THEREOF
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Paragraph 00145, (2020/07/31)
Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.
A new efficient synthesis of ω-aminoalkylidene-1,1-bisphosphonate tetraethylesters
Gourves, Jean-Philippe,Couthon, Helene,Sturtz, Georges
, p. 219 - 229 (2007/10/03)
Bisphosphonates are interesting therapeutic agents in the management of bone diseases and since several years our laboratory has been developing the chemistry of 1,1-bisphosphonates. This paper describes an original synthesis of two aminoalkylidenebisphosphonates by first preparing the intermediate hydroxyalkylidenebisphosphonates which are transformed into amines via the azides.
PHOSPHONATE DERIVATIVES OF LIPOPHILIC AMINES
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, (2008/06/13)
This invention relates to a class of novel phosphonate derivatives of lipophilic amines which exhibit squalene synthase inhibition properties. More specifically the compounds are bis aryl cycloalkylamino and azacycloalkyl phosphonates. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.
