151699-35-3Relevant articles and documents
Asymmetric total synthesis, X-ray crystallography, and preliminary biological evaluation of 1-(1'-hydroxyethyl)-25-hydroxyvitamin D3 analogs of natural calcitriol
Posner,Dai,Afarinkia,Narasimha Murthy,Guyton,Kensler
, p. 7209 - 7215 (1993)
With 3-bromo-2-pyrone as diene and acrolein as dienothile, thermally mild Diels-Alder cycloaddition led to an isolable bicyclic lactone aldehyde that underwent highly stereocontrolled methyl Grignard addition to form essentially only a single diastereomer