151707-31-2Relevant academic research and scientific papers
Synthesis of 1-O-Acylglycerol 2,3-Cyclic Phosphate: Determination of the Absolute Structure of PHYLPA, A Specific Inhibitor of DNA Polymerase α
Kabayashi, Susumu,Tokunoh, Ryosuke,Shibasaki, Masakatsu,Shinagawa, Rumi,Murakami-Murofushi, Kimiko
, p. 4047 - 4050 (2007/10/02)
Four possible stereoisomers of PHYLPA, a specific inhibitor of DNA polymerase α, were synthesized in enantioselective manners.These isomers were examined for inhibition activity for DNA polymerase α, and the structure of PHYLPA was established as sodium 1-O--sn-glycerol 2,3-cyclic phosphate.
