151724-40-2Relevant academic research and scientific papers
CYCLOADDITION REACTIONS WITH AZABENZENES. XVIII. SYNTHESIS OF PYRINDINES
Neunhoeffer, Hans,Philipp, Bernd,Schildhauer, Birgit,Eckrich, Ralf,Krichbaum, Uwe
, p. 1089 - 1101 (2007/10/02)
The reaction of 1,2,4-triazines (1) and 1-cyclopentenylpyrrolidine (2) afforded 6,7-dihydro-5H--pyrindines (3) in good yields.Oxidation of 3 to the N-oxides (4), reaction of 4 with acetic anhydride to 5-acetoxy-6,7-dihydro-5H-pyrindines (5) and elimination of acetic acid afforded pyrindines (7). 2-Methyl-2H-pyrindines (9) were also prepared.
