151729-42-9

Basic information

• Product Name: 2-aMino-4-(trifluoroMethyl)thiazole-5-carbonitrile
• Synonyms: 2-aMino-4-(trifluoroMethyl)thiazole-5-carbonitrile;2-Amino-5-cyano-4-trifluoromethylthiazole
• CAS NO: 151729-42-9
• Molecular Formula: C₅H₂F₃N₃S
• Molecular Weight: 193.1496896
• Mol File: 151729-42-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.62
• CAS DataBase Reference: 2-aMino-4-(trifluoroMethyl)thiazole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aMino-4-(trifluoroMethyl)thiazole-5-carbonitrile(151729-42-9)
• EPA Substance Registry System: 2-aMino-4-(trifluoroMethyl)thiazole-5-carbonitrile(151729-42-9)

Safety Data

• Hazardous Substances Data: 151729-42-9(Hazardous Substances Data)

Usage

Structure

Thiazole derivative with a carbonitrile group attached to the thiazole ring

Functional Groups

Amino group (2-amino)
Trifluoromethyl group (trifluoromethyl)
Carbonitrile group (carbonitrile)

Potential Applications

Pharmaceutical industry

Scaffold

Found in various bioactive molecules

Enhancement Properties

Trifluoromethyl group enhances:
Lipophilicity
Metabolic stability

Derivatization Potential

Amino and carbonitrile groups can be utilized for further derivatization

Use in Drug Development

Potential for developing new drugs and pharmaceutical products

Upstream product

• 151729-41-8 2-chloro-5-cyano-4-trifluoromethylthiazole 

Downstream Products

• 901306-17-0 2-(2-(2-tert-butylphenoxy)pyridin-3-ylamino)-4-(trifluoromethyl)thiazole-5-carbonitrile 

Relevant articles and documents

Amino thiazole derivatives and their use as fungicides

A thiazole derivative represented by the following formula (I): wherein the all symbols are defined in the description, and a fungicide composition comprising the thiazole derivative and a carrier are disclosed.