151763-89-2

Basic information

• Product Name: (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE
• Synonyms: (8aR)-Hexahydro-pyrrolo[1,2-a]pyrazin-6(2H)-one hydrochloride;(R)-Hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one;(R)-tetrahydropyrrolo1,2-apyrazin-6(1H,2H,7H)-one;Pyrrolo[1,2-a]pyrazin-6(2H)-one, hexahydro-, (8aR)-;(R)-Hexahydro-pyrrolo[1,2-a]pyrazin-6(2H)-one hydrochloride;(R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE;(8aR)-hexahydro-Pyrrolo[1,2-a]pyrazin-6(2H)-one;(8aR)-octahydropyrrolo[1,2-a]piperazin-6-one
• CAS NO: 151763-89-2
• Molecular Formula: C₇H₁₂N₂O
• Molecular Weight: 140.18
• Mol File: 151763-89-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 284.4±29.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 8.32±0.20(Predicted)
• CAS DataBase Reference: (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE(151763-89-2)
• EPA Substance Registry System: (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE(151763-89-2)

Safety Data

• Hazardous Substances Data: 151763-89-2(Hazardous Substances Data)

Usage

Description

(R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE is a heterocyclic organic compound characterized by its molecular formula C7H11N3O. It features a unique structure that includes nitrogen and oxygen atoms, which contribute to its diverse properties and applications. (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE is particularly notable for its role as a key intermediate in the pharmaceutical industry, where it is utilized in the development of medications targeting the central nervous system.

Uses

Used in Pharmaceutical Industry:
(R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE is used as a key intermediate in the synthesis of various pharmaceuticals, particularly those aimed at treating conditions related to the central nervous system. Its unique structure allows it to be a versatile component in the creation of anxiolytics, sedatives, and anticonvulsants, making it an essential compound in medicinal chemistry.
Used in Agrochemicals:
Beyond its applications in human healthcare, (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE also shows promise in the agrochemical industry. Its potential uses in this field could include the development of compounds for pest control or crop protection, leveraging its chemical properties to enhance agricultural productivity and sustainability.
Used in Other Industries:
(R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE's diverse properties suggest that it may also find applications in other industries beyond pharmaceuticals and agrochemicals. While specific uses have not been detailed in the provided materials, the potential for (R)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-6-ONE to be employed in areas such as materials science, chemical research, or even as a component in the development of new technologies, remains an open possibility due to its unique characteristics.

Upstream product

• 865717-09-5 (R)-(+)-2-benzylhexahydropyrrolo[1,2-a]pyrazin-6(7H)-one 

Downstream Products

• 1182733-10-3 (R)-2-(2-fluorobenzenesulfonyl)hexahydropyrrolo[1,2-a]pyrazin-6-one 
• 930782-61-9 (8aR)-2-[1-(diphenylmethyl)azetidin-3-yl]hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one 

Relevant articles and documents

Nitrogen-containing bicyclic compounds active on chronic pain conditions

The invention refers to compounds of general formula (I) wherein the R groups are, independently, H, C1-6alkyl, aryl, CF3; Y is CH2, C=O; X is bond, C=O, SO2, or C=N-CN; m is 0, 1; n is 0, 1; A is a heterocycle, or a phenyl group optionally substituted. The compounds are active on chronic pain conditions of different origin; they can be administered alone or with other drugs. Most of these compounds are new. The invention include a process to prepare said compounds, and pharmaceutical compositions suitable for their administration to a patient.