15178-63-9 Usage
Description
4-MALEIMIDO-TEMPO, also known as 4-Maleimido-2,2,6,6,-tetramethylpiperidinooxyl, is a water-soluble nitroxide radical commonly used as a spin probe. It is characterized by its red-orange solid appearance and has been reported to inhibit the survival of CHO cells at 1mM concentrations. 4-MALEIMIDO-TEMPO is widely used as a maleimide spin label for electron paramagnetic resonance (EPR) studies.
Uses
Used in EPR Studies:
4-MALEIMIDO-TEMPO is used as a thiol-specific spin label for EPR studies to investigate various interactions and influences on biological membranes. It is particularly useful for studying the effects of bile salts on intact rat mitochondrial membranes and the interaction of quercetin with erythrocyte proteins by EPR spectra.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-MALEIMIDO-TEMPO is used as a spin label for the labeling of erythrocyte membranes, which aids in the study of protein interactions and the development of new drugs and therapies.
Used in Chemical Research:
4-MALEIMIDO-TEMPO is also employed in chemical research as a spin probe to study the properties and behavior of various molecules and compounds, contributing to the advancement of chemical knowledge and the development of new materials and applications.
Biochem/physiol Actions
Spin label used to study fluidity of brain synaptosomal membranes, internal microviscosity of erythrocytes, and human high density lipoproteins.
Check Digit Verification of cas no
The CAS Registry Mumber 15178-63-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,7 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15178-63:
(7*1)+(6*5)+(5*1)+(4*7)+(3*8)+(2*6)+(1*3)=109
109 % 10 = 9
So 15178-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H19N2O3/c1-12(2)7-9(8-13(3,4)15(12)18)14-10(16)5-6-11(14)17/h5-6,9H,7-8H2,1-4H3/q-1
