15180-00-4Relevant articles and documents
Chemical synthesis technology for prednisolone valerate acetate
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Paragraph 0049; 0053; 0054; 0058; 0062; 0063; 0067; 0071, (2019/04/26)
The invention belongs to the technical field of chemical synthesis, and discloses a chemical synthesis technology for prednisolone valerate acetate. With prednisolone, para-toluenesulfonic acid, trimethyl orthovalerate, dimethylaminopyridine, pyridine and acetic anhydride being raw materials, the prednisolone valerate acetate is synthesized through a few technological steps; in this way, the production process is simplified, production costs are remarkably lowered, the yield is high, product purity is high, and the chemical synthesis technology is suitable for large-scale production of factories, and has good industrial development value and good market application prospects.
An improved synthesis of corticosteroid 17α-esters by synthetic aluminium silicate-mediated conversion of 17α, 21-cyclic ortho esters
Sugai,Okazaki,Akaboshi
, p. 700 - 701 (2007/10/02)
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