151803-47-3Relevant articles and documents
Synthesis of a tetrasaccharide repeating unit of the exopolysaccharide from Burkholderia multivorans
Zhang, Xin,Wang, Dongyue,Jin, Guoxia,Wang, Lizhen,Guo, Zhongwu,Gu, Guofeng
, p. 189 - 204 (2017)
The chemical synthesis of a tetrasaccharide repeating unit of the exopolysaccharide discovered from Burkholderia multivorans with a 3-aminopropyl group linked to the glycan downstream end, α-D-Manp-(1→2)-α-D-Manp-(1→2)-3-O-methyl-α-DRhap-(1→3)-α-D-Rhap-O(CH2)3NH2 (1), was described. The target tetrasaccharide was achieved by both a convergent [2 + 2] and a linear glycosylation strategies. The latter synthesis was proved to be more efficient than the former due to the excellent stereocontrol of glycosylation. Furthermore, the 3-aminopropyl group in the target molecule would enable its conjugation with functional biomolecules to explore its biological applications.