151803-47-3Relevant academic research and scientific papers
Synthesis of a tetrasaccharide repeating unit of the exopolysaccharide from Burkholderia multivorans
Zhang, Xin,Wang, Dongyue,Jin, Guoxia,Wang, Lizhen,Guo, Zhongwu,Gu, Guofeng
, p. 189 - 204 (2017)
The chemical synthesis of a tetrasaccharide repeating unit of the exopolysaccharide discovered from Burkholderia multivorans with a 3-aminopropyl group linked to the glycan downstream end, α-D-Manp-(1→2)-α-D-Manp-(1→2)-3-O-methyl-α-DRhap-(1→3)-α-D-Rhap-O(CH2)3NH2 (1), was described. The target tetrasaccharide was achieved by both a convergent [2 + 2] and a linear glycosylation strategies. The latter synthesis was proved to be more efficient than the former due to the excellent stereocontrol of glycosylation. Furthermore, the 3-aminopropyl group in the target molecule would enable its conjugation with functional biomolecules to explore its biological applications.
Investigation of Different Synthetic Approaches towards Methyl 2,6-Dideoxy-α-D-arabino- and -α-D-lyxo-hexopyranosides
Kjoelberg, Ove,Neumann, Klaus
, p. 721 - 727 (2007/10/02)
New synthetic routes for making available different methyl 2,6-dideoxyhexopyranosides are reported.Starting with methyl 6-deoxy-2,3-O-isopropylidene-α-D-manno- and -α-D-talo-pyranoside the respective methyl 2,6-dideoxy-α-D-arabino- and α-D-lyxo-hexopyrano
