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Sulfurous acid is a light-colored, aqueous solution that contains the HO3S radical. It is known for its ability to cause severe burns to skin, eyes, and mucous membranes. Despite its corrosive nature, sulfurous acid is noncombustible and can be identified by its technical name found on shipping papers.

15181-46-1

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15181-46-1 Usage

Uses

Used in Anticancer Applications:
Sulfurous acid is used as an anticancer agent, particularly against solid malignancies such as liver, breast, lung, pancreatic, colorectal, and ovarian cancers. It modulates several oncological signaling pathways, including JAK/STAT, RAS/RAF/mTOR, TGF-β1/TGF-β1R, VEGF/VEGFR, and CXCL12/CXCR4 axes, exerting inhibitory effects on tumor growth and progression. Additionally, sulfurous acid demonstrates synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Drug Delivery Systems:
To overcome the limitations of sulfurous acid, novel drug delivery systems have been developed to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles have been employed as carriers for sulfurous acid delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.
Used in Chemical Industry:
Sulfurous acid is used as a preservative and disinfectant in the chemical industry due to its ability to inhibit the growth of microorganisms and prevent spoilage. Its antimicrobial properties make it suitable for use in various applications, such as preserving food products and treating water supplies.
Used in Paper Industry:
In the paper industry, sulfurous acid is used as a bleaching agent for pulp and paper production. Its ability to break down lignin and brighten the pulp makes it an essential component in the manufacturing process of various paper products.
Used in Textile Industry:
Sulfurous acid is utilized in the textile industry for its ability to remove impurities and stains from fabrics during the bleaching process. Its effectiveness in whitening and brightening textiles makes it a valuable resource for the production of high-quality fabrics.
Used in Wine Industry:
In the wine industry, sulfurous acid is used as an antimicrobial agent to prevent the growth of unwanted microorganisms and maintain the quality of the wine. Its ability to inhibit spoilage and preserve the taste of the wine makes it a crucial component in the winemaking process.
Used in Rubber Industry:
Sulfurous acid is employed in the rubber industry as an accelerator in the vulcanization process. Its ability to speed up the curing of rubber compounds contributes to the production of more durable and long-lasting rubber products.

Reactivity Profile

When heated to decomposition or on contact with mineral acids sulfurous acid emits highly toxic fumes of sulfur dioxide gas [Sax, 9th ed., 1996, p. 2949].

Hazard

Questionable carcinogen.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Check Digit Verification of cas no

The CAS Registry Mumber 15181-46-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,8 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15181-46:
(7*1)+(6*5)+(5*1)+(4*8)+(3*1)+(2*4)+(1*6)=91
91 % 10 = 1
So 15181-46-1 is a valid CAS Registry Number.
InChI:InChI=1/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1

15181-46-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name hydrogensulfite

1.2 Other means of identification

Product number -
Other names Bisulfite

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15181-46-1 SDS

15181-46-1Upstream product

15181-46-1Downstream Products

15181-46-1Related news

sulfurous acid (cas 15181-46-1) (H2SO3) on Io?08/01/2019

Sulfurous acid (H2SO3) has never been characterized or isolated on Earth. This is caused by the unfavorable conditions for H2SO3 within Earth's atmosphere due to the high temperatures, the high water content and the oxidizing environment. Kinetic investigations by means of transition state ...detailed

Free sulfurous acid (cas 15181-46-1) (FSA) inhibition of biological thiosulfate reduction (BTR) in the sulfur cycle-driven wastewater treatment process07/31/2019

A sulfur cycle-based bioprocess for co-treatment of wet flue gas desulfurization (WFGD) wastes with freshwater sewage has been developed. In this process the removal of organic carbon is mainly associated with biological sulfate or sulfite reduction. Thiosulfate is a major intermediate during bi...detailed

Cytotoxicity of sulfurous acid (cas 15181-46-1) on cell membrane and Bioactivity of Nitrosomonas europaea07/29/2019

Nitrosomonas europaea, an ammonia oxidizing bacterium, was chosen as a research model to study the alteration of cell membrane in the presence of sulfurous acid and biodegradation of acetochlor. Significant changes of the outer cell membrane were observed in the presence of sulfurous acid using ...detailed

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