15181-86-9Relevant articles and documents
Formation and reductive ring opening reactions of indolyl-isoxazolidines: Access to novel natural product analogs and precursors
Singh, Gagandeep,Sharma, Suresh,Gupta, Vivek,Raj, Tilak,Singh, Palwinder,Ishar, Mohan Paul S.
, p. 900 - 911 (2016)
Regio- and stereoselective 1,3-dipolar cycloadditions of C-(3-indolyl)-N-phenylnitrone (2) with variedly substituted dipolarophiles were carried out to obtain syn- C4 and C5 substituted indolyl-isoxazolidines 6a-c and 7a-f, respectively. Reduction of obtained isoxazolidines, by employing various reducing agents, causes cleavage of the N-O bond, which is accompanied by concomitant cleavage of C-N bond leading to the formation of a library of novel indole based natural product analogs and precursors.
NEW Cs2CO3 CATALYST FOR THE WIITIG-HORNER SYNTHESIS OF ACRYLATES IN INTERFACIAL SOLID LIQUID CONDITIONS
Sinisterra, J. V.,Barrios, J.,Mouloungui, Z.,Delmas, M.,Gaset, A.
, p. 267 - 275 (2007/10/02)
Cesium carbonate is described as an efficient catalyst for the Wittig-Horner reaction in interfacial solid-liquid conditions.This solid is more effective catalyst than potassium carbonate or activated barium hydroxide catalyst (C-200), under the same experimental conditions.Phenolic aldehydes or aldehydes with N-H group can only carry to acrylate in the presence of cesium carbonate.These aldehydes are not reactive when potassium carbonate or C-200 are used as catalysts.The synthetic method is described and the influence of the cesium carbonate structure on the yield is discussed.The mechanism of the reaction is qualitatively described in terms of the nature of the adsorbed species and the influence of the solid cell lattice on the yield.The difference in the catalytic activity observed in the solid bases tested is discussed on the basis of an interfacial solid-liquid mechanism.
