151851-70-6 Usage
Uses
Used in Pharmaceutical Industry:
Eszopiclone N-Oxide is used as a metabolite for Eszopiclone, which is a nonbenzodiazepine sedative-hypnotic drug. It plays a role in the metabolism and pharmacological effects of Eszopiclone, potentially contributing to the overall efficacy and safety profile of the drug in the treatment of insomnia.
Used in Research and Development:
As a metabolite of Eszopiclone, Eszopiclone N-Oxide may be used in research and development for understanding the metabolic pathways and pharmacokinetics of Eszopiclone. This knowledge can be applied to optimize drug formulations, improve drug delivery, and enhance the therapeutic effects of Eszopiclone in the treatment of insomnia.
Used in Quality Control and Analysis:
Eszopiclone N-Oxide, being a metabolite of Eszopiclone, can be used in the quality control and analysis of pharmaceutical products containing Eszopiclone. It can help in the identification, quantification, and assessment of the purity of Eszopiclone in various drug formulations, ensuring the safety and efficacy of the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 151851-70-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,8,5 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 151851-70:
(8*1)+(7*5)+(6*1)+(5*8)+(4*5)+(3*1)+(2*7)+(1*0)=126
126 % 10 = 6
So 151851-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H17ClN6O4/c1-24(27)8-6-22(7-9-24)17(26)28-16-14-13(19-4-5-20-14)15(25)23(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
151851-70-6Relevant articles and documents
Spectrophotometric determination of eszopiclone in pure and pharmaceutical forms
Chennaiah,Veeraiah,Venkateshwarlu
, p. 1460 - 1463 (2012)
Six spectrophotometric methods for determination of eszopiclone have been developed, validated and applied for the assay of the drug in pharmaceuticals. Methods A, B, C and D are based on ion pair complexation of drug, in acidic buffers, with triphenylmethane dyes viz., Bromothymol blue(BTB), Bromophenol blue(BPB), Bromocresol green(BCG) and Bromocresol purple(BCP). The complexes are extracted into chloroform and absorbance is measured around at 415 nm as function of concentration of the drug. The stoichiometry of the complex is found 1:1 in each case. Method E depends upon charge transfer complexation of neutralized drug with iodine which produces iodide ion whose absorbance at 366 nm is measured as function of concentration of the drug. This complex, too, has 1:1 composition as determined by Job's method. Method F is developed on the basis of oxidation of the drug with alkaline KMnO4 which generates green colored manganate ion with lmax 610 nm. As the intensity of green color increased with increasing time kinetics of the reaction is followed and calibration curves are constructed by using initial rate and fixed time methods. Excellent recovery studies with high accuracy and precession indicate that the methods can be successfully used in industries for the assay of drug in pure form and pharmaceuticals.
