151872-17-2Relevant articles and documents
Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target
Watson, Gabrielle M.,Gunzburg, Menachem J.,Ambaye, Nigus D.,Lucas, William A. H.,Traore, Daouda A.,Kulkarni, Ketav,Cergol, Katie M.,Payne, Richard J.,Panjikar, Santosh,Pero, Stephanie C.,Perlmutter, Patrick,Wilce, Matthew C. J.,Wilce, Jacqueline A.
, p. 7707 - 7718 (2015)
The Grb7 adaptor protein is a therapeutic target for both TNBC and HER2+ breast cancer. A nonphosphorylated cyclic peptide 1 (known as G7-18NATE) inhibits Grb7 via targeting the Grb7-SH2 domain, but requires the presence of phosphate ions for both affinit
Type b botulism toxin inhibitors
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Page 9, (2010/02/08)
The invention relates to novel compounds of genera formula (I), with inhibitory properties for the type B botulism toxin activity, the methods for preparation thereof and corresponding pharmaceutical compositions. The invention further relates to correspo
