151879-73-1 Usage
Uses
Treatment of non-small
cell lung cancer (antisense oligonucleotide; protein kinase
C-alpha inhibitor).
Brand name
Affinitak (Isis).
Clinical Use
Aprinocarsen is a phosphorothioate antisense agent targeted against protein kinase Cα,
a protein that is implicated in malignant transformation and proliferation. It showed
activity in Phase I and Phase II clinical trials against nonsmall-cell lung cancer when
used in combination with cisplatin or the combination of cisplatin and gemcitabine.
Check Digit Verification of cas no
The CAS Registry Mumber 151879-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,8,7 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 151879-73:
(8*1)+(7*5)+(6*1)+(5*8)+(4*7)+(3*9)+(2*7)+(1*3)=161
161 % 10 = 1
So 151879-73-1 is a valid CAS Registry Number.