151885-83-5Relevant academic research and scientific papers
A convenient synthesis of 2-amino-3-cyano-4-aryl-1,4,5,6-tetrahydrobenzo[h] chromenes derivatives using KF-Al2O3 as catalyst
Wang, Xiang-Shan,Zeng, Zhao-Sen,Shi, Da-Qing,Wei, Xian-Yong,Zong, Zhi-Min
, p. 3265 - 3271 (2007/10/03)
A series of new 2-amino-3-cyano-4-aryl-1,4,5,6-tetrahydrobenzo[h]chromenes derivatives were synthesized by the reaction of malononitrile with 2-arylmethylidene-3, 4-dihydro-1(2H)-naphthalenone in N,N-dimethylformamide (DMF) at 80°C catalyzed by KF-Al2O3. The structure of the product was confirmed by x-ray analysis.
Pharmaceutical compounds
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, (2008/06/13)
The invention provides pharmaceutical compounds of the formula: STR1 in which A - - - B is CH2 --CH2 or CH=CH; X is a pyridine or benzene ring; when X is pyridine n is 0; when X is benzene n is 0, 1 or 2 and when A - - - B is CH
Therapy for diabetic complications
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, (2008/06/13)
This invention provides a method of treating diabetic complications in mammals which comprises the administration of a compound of the Formula I: STR1 in which n, R1, R2, R3, and R4 are variables.
Methods of using dihydropyrans
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, (2008/06/13)
Methods of treating an immune disease, cell proliferation, restenosis and vascular smooth muscle cells using the pharmaceutical compounds of the formula STR1 in which R2 is phenyl, naphthyl or heteroaryl selected from thienyl, pyridyl, benzothi
