151886-09-8

Basic information

• Product Name: 2-amino-4-(2-thienyl)-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile
• Synonyms: 2-amino-4-(2-thienyl)-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile
• CAS NO: 151886-09-8
• Molecular Formula: C18H14N2OS
• Molecular Weight: 306.38156
• Mol File: 151886-09-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-4-(2-thienyl)-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(2-thienyl)-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile(151886-09-8)
• EPA Substance Registry System: 2-amino-4-(2-thienyl)-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile(151886-09-8)

Safety Data

• Hazardous Substances Data: 151886-09-8(Hazardous Substances Data)

Upstream product

• 106368-03-0 (E)-2-(thiophen-2-ylmethylene)-3,4-dihydronaphthalen-1-(2H)-one 
• 109-77-3 malononitrile 

Downstream Products

• 272775-24-3 2-ethoxy-4-(2-thienyl)-5,6-dihydrobenzo[h]quinoline-3-carbonitrile 

Relevant articles and documents

Synthetic approaches towards benzo[h]quinoline-3-carbonitriles

2-Alkoxybenzo[h]quinoline-3-carbonitriles 2 were readily synthesized via Dimroth rearrangement of 2-amino-4-aryl-5,6-dihydro-4H-naphtho[1,2-b]pyran-3- carbonitriles 5 induced by ethanolic and methanolic KOH. Compounds 2 were also obtained by the reaction of 2-arylmethylidene-3,4-dihydro-1(2H)- naphthalenones 1 with malononitrile or of ylidenemalononitriles 4 with 1,2,3,4-tetrahydro-1-naphthalenone in ethanolic and methanolic KOH. The molluscicidal activity of the products towards Biomphalaria alexandrina snails was screened.