151915-18-3

Upstream product

• 151915-16-1 (S)-(+)-Dihydro-5-<(E)-1,3-butadienyl>-2(3H)-furanone 
• 75629-74-2 (S)-(-)-Tetrahydro-5-oxo-2-furancarboxaldehyde 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 111467-60-8 (1S,2R,8R,8aS)-octahydro-1,2,8-indolizidinetriol 
• 72741-87-8 (1S,2R,8S,8aS)-octahydro-1,2,8-indolizidinetriol 
• 85624-09-5 (1S,2R,8S,8aS)-8-hydroxy-1,2-O-iso-propylideneoctahydro-1,2,8-indolizidine triol 
• 105888-90-2 Benzoic acid (3aR,9R,9aS,9bS)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-a]indolizin-9-yl ester 
• 151915-20-7 (S)-(-)-4-<(tert-Butyldiphenylsilyl)oxy>-5(E),7-octadienohydroxamic acid 
• 151915-24-1 N-Succinimidyl 4(S)-<(tert-butyldiphenylsilyl)oxy>-5(E),7-octadienoate 
• 152005-79-3 (5S,8S,8aS)-5-<(tert-Butyldiphenylsilyl)oxy>pyrido<1,2-b><1,2>oxazin-8-one 
• 151915-21-8 (5S,8S,8aR)-5-<(tert-Butyldiphenylsilyl)oxy>pyrido<1,2-b><1,2>oxazin-8-one 
• 151915-25-2 (5S,6R)-5-(tert-Butyl-diphenyl-silanyloxy)-6-((4S,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-piperidin-2-one 
• 152005-88-4 (5S,6S)-5-(tert-Butyl-diphenyl-silanyloxy)-6-((4R,5S)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-piperidin-2-one 
• 151915-26-3 Methanesulfonic acid (4R,5S)-5-[(2R,3S)-3-(tert-butyl-diphenyl-silanyloxy)-6-oxo-piperidin-2-yl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 152005-89-5 Methanesulfonic acid (4S,5R)-5-[(2S,3S)-3-(tert-butyl-diphenyl-silanyloxy)-6-oxo-piperidin-2-yl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 151915-19-4 (S)-(-)-4-<(tert-Butyldiphenylsilyl)oxy>-5(E),7-octadienoic acid 

Relevant academic research and scientific papers

An Acylnitroso Cycloaddition Approach to the Synthesis of Highly Oxygenated Indolizidine Alkaloids

A synthetic approach to the synthesis of highly oxygenated indolizidine alkaloids is described.A key feature of the approach is intramolecular cycloaddition between an acylnitroso dienophile and a tethered diene moiety, followed by ring contraction of the 1,2-oxazine so formed to a pyrrolidine.The requisite intermediates were prepared in optically pure form from L-glutamic acid.