151929-40-7Relevant academic research and scientific papers
Asymmetric Synthesis of Both Enantiomers of Vigabatrin: An Approach Using Methionine as the Chiral Pool
Wei, Zhong-Yong,Knaus, Edward E.
, p. 5569 - 5578 (1994)
Both enantiomers of the potent GABA-T inhibitor, 4-amino-5-hexenoic acid (2), were prepared in five steps from (R)- or (S)-methionine using a one-pot reduction-homologation of an α-amino ester as the key reaction step.
