1520078-16-3

Basic information

• Product Name: 3-methoxy-7-nitro-2-phenylquinazolin-4(3H)-one
• Synonyms: 3-methoxy-7-nitro-2-phenylquinazolin-4(3H)-one
• CAS NO: 1520078-16-3
• Molecular Weight: 297.27
• Mol File: 1520078-16-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methoxy-7-nitro-2-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-7-nitro-2-phenylquinazolin-4(3H)-one(1520078-16-3)
• EPA Substance Registry System: 3-methoxy-7-nitro-2-phenylquinazolin-4(3H)-one(1520078-16-3)

Safety Data

• Hazardous Substances Data: 1520078-16-3(Hazardous Substances Data)

Upstream product

• 1520077-97-7 2-amino-N-methoxy-4-nitrobenzamide 
• 63480-10-4 4-nitroisatoic anhydride 

Relevant articles and documents

One-pot synthesis of quinazolinones from anthranilamides and aldehydes via p -toluenesulfonic acid catalyzed cyclocondensation and phenyliodine diacetate mediated oxidative dehydrogenation

A variety of 4(3H)-quinazolinones are synthesized conveniently in one pot from 2-aminobenzamides and aldehydes, via cyclization catalyzed by p-toluenesulfonic acid followed by oxidative dehydrogenation mediated by the hypervalent iodine compound phenyliodine diacetate [PhI(OAc)2, PIDA]. Highlights of the described method include the first synthesis of quinazolinones bearing an N-alkoxy substituent, a new application of phenyliodine diacetate as an efficient dehydrogenative oxidant, and mild reaction conditions. Georg Thieme Verlag Stuttgart, New York.