15212-80-3

Usage

Derivative of 1,2,3-triazole

The compound is based on the 1,2,3-triazole core structure, which is a five-membered heterocyclic ring containing three nitrogen atoms.

Presence of a benzyl group

The molecule contains a benzyl group (C6H5CH2-), which is a phenyl group attached to a methylene group (-CH2-).

Presence of a chloro group

The compound has a chlorine atom (Cl) attached to the benzyl group, which can influence its reactivity and properties.

Carboxylic acid functional group

The molecule contains a carboxylic acid group (-COOH), which imparts acidic properties to the compound.

Potential applications

This chemical may have potential uses in pharmaceuticals, agrochemicals, and materials science due to its unique structural properties.

Building block for synthesis

The compound could be used as a building block for the synthesis of more complex molecules, contributing to the development of new drugs or materials.

Reagent in organic chemistry reactions

The presence of various functional groups makes it a potential reagent in organic chemistry reactions, facilitating the formation of new bonds and structures.

Unique properties from the 1,2,3-triazole core

The presence of the 1,2,3-triazole core in the molecule may confer unique properties that can be utilized in various chemical processes, such as catalysis or ligand binding.

Upstream product

• 75020-50-7 ethyl 1-benzyl-5-chloro-1H-1,2,3-triazole-4-carboxylate 
• 622-79-7 benzyl azide 
• 100-44-7 benzyl chloride 
• 94158-08-4 Ethyl 1-phenylmethyl-5-hydroxy-1,2,3-triazole-4-carboxylate 

Downstream Products

• 129609-28-5 5,6,7,8-tetrahydro-4-phenyl-3-(phenylmethyl)-3H-1,2,3-triazolo<4,5-b>quinolin-9(4H)-one 
• 129609-23-0 <2-(Phenylamino)-1-cyclohexen-1-yl><5-chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl>methanone 
• 129609-39-8 <5-Chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl><2,5-dihydro-4-(phenylamino)-3-thienyl>methanone 
• 129609-44-5 8-Phenyl-1,5,7,8-tetrahydro-1-(phenylmethyl)-4H-thieno<3,4-e>-1,2,3-triazolo<4,5-b>pyridin-4-one 
• 129609-45-6 8-Phenyl-1,8-dihydro-1-(phenylmethyl)-4H-thieno<3,4-e>-1,2,3-triazolo<4,5-b>pyridin-4-one 
• 129609-27-4 3-Phenylmethyl-4-phenyl-8-oxo-4,5,6,7-tetrahydrocyclopenta-1,2,3-triazolo<4,5-e>pyridine 
• 129609-20-7 <5-Chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl><2-(1-pyrrolidinyl)-1-cyclohexen-1-yl>methanone 
• 129609-22-9 <2-(Phenylamino)-1-cyclopenten-1-yl><5-chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl>methanone 
• 129609-19-4 <5-Chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl><2-(1-pyrrolidinyl)-1-cyclopenten-1-yl>methanone 
• 129609-37-6 <5-Chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl>(4,5-dihydro-3-hydroxy-2-thienyl)methanone 
• 129609-38-7 <5-Chloro-1-(phenylmethyl)-1H-1,2,3-triazol-4-yl>(2,5-dihydro-4-hydroxy-3-thienyl)methanone 
• 96938-84-0 1-Benzyl-5-chloro-4-(2-hydroxy-4-methoxy-3-methylbenzoyl)-1H-1,2,3-triazole 
• 96938-83-9 1-Benzyl-5-chloro-4-(2-hydroxy-4-methoxybenzoyl)-1H-1,2,3-triazole 
• 96938-88-4 3-Benzyl-6-methoxy-5-methyl-9-oxo-3H,9H-benzopyrano<2,3-d>-1,2,3-triazole 

Relevant academic research and scientific papers

Transaminations of Enaminones: A Synthesis of Tricyclic, N-Aryl, 1,2,3-Triazole-fused Pyridones

1-Phenylmethyl- and 1-(4-methoxyphenylmethyl)-5-chloro-1,2,3-triazole-4-carbonyl chlorides acylated the pyrrolidine enamines of cyclopentanone and cyclohexanone, and the resulting enaminones underwent transaminations with aryl amines under acidic conditions.The products then cyclized under basic conditions to linearly fused, tricyclic 3-phenylmethyl- and 3-(4-methoxyphenylmethyl)-4-aryl-8-oxo-4,5,6,7-tetrahydrocyclopenta-1,2,3-triazolopyridines, and to 5,6,7,8-tetrahydro-4-aryl-3H-1,2,3-triazoloquinolin-9(4H)-ones.Similar transaminations afforded the related 8-phenyl- and 8-(3-chlorophenyl)-1,5,7,8-tetrahydro-1-(phenylmethyl)-4H-thieno-1,2,3-triazolopyridin-4-ones.Phase-transfer and catalytic hydrogenolyses of some of these intermediates furnished 4-aryl-8-oxo-4,5,6,7-tetrahydrocyclopenta-1,2,3-triazolopyridines and 4-aryl-5,6,7,8-tetrahydro-3H-1,2,3-triazoloquinoline-9(4H)-ones.The 3-(4-methoxyphenylmethyl)-4-aryl intermediates were sterically crowded.Two protons from the methoxyphenylmethylphenylmethylgroups were dramatically shielded because of anisotropic effects exerted by the 4-aryl substituents.

Studies on 1,2,3-Triazoles. Part XI. A New Entry to the Benzopyrano-1,2,3-triazole System. Cyclization of 1-Benzyl-5-chloro-4-(2-hydroxybenzoyl)-1H-1,2,3-triazoles

The acylation of simple arenes such as benzene and alkylated benzenes with N-protected 5-chloro-1H-1,2,3-triazole-4-carboxylic acid chlorides under Friedel-Crafts conditions results in excellent yields of the corresponding ketones.Resorcinol dimethyl ethe