152121-79-4Relevant academic research and scientific papers
Treatment for CNS injuries
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, (2008/06/13)
The present invention is directed to the use of 2,4,5-trisubstituted imidazole compounds and compositions in the treatment of CNS injuries to the brain.
Use of kinase inhibitors for treating neurodegenerative diseases
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, (2008/06/13)
The present invention relates to methods of treating neurodegenerative diseases, including but not limited to Parkinson's disease. In particular, the present invention provides methods utilizing the administration of pyridyl imidazoles having simultaneous inhibitory activity towards p38 mitogen-activated protein (MAP) kinase and c-jun-N-terminal kinase (JNK). The present invention also provides methods for preventing apoptosis of dopamine neurons using pyridyl imidazoles. The present invention also provides methods for the treatment of neurodegenerative diseases, including but not limited to Parkinson's disease.
Pyrimidinyl imidazoles
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, (2008/06/13)
Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
Imidazole derivatives and their use as cytokine inhibitors
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, (2008/06/13)
As cytokine inhibitors 2,4,5-triarylimidazole compounds and compositions for use as cytokine inhibitors.
Pyridyl imidazoles
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, (2008/06/13)
Novel 2,4,5-triaryl imidazole compounds and compositions for use in therapy.
