15216-91-8Relevant academic research and scientific papers
Rapid total synthesis of (±)trigonoliimine A via a Strecker/Houben-Hoesch sequence
Zhao, Bing,Hao, Xiao-Yan,Zhang, Jian-Xin,Liu, Sheng,Hao, Xiao-Jiang
, p. 528 - 530 (2013)
A novel synthetic route to the hexacyclic system of trigonoliimine A was accomplished in four steps from N-phthaloyl 6-OMe-tryptamine. Key reactions include a three-component Strecker-type reaction to fashion the two C-N bonds in the D ring and a subsequent Houben-Hoesch type cyclization to deliver the characteristic seven-membered C ring.
