152187-38-7

Usage

Chemical structure

A flavonolignan compound derived from the milk thistle plant (Silybum marianum).

Source

Milk thistle plant (Silybum marianum).

Antioxidant properties

Exhibits antioxidant activity, which helps neutralize harmful free radicals.

Anti-inflammatory properties

Demonstrates anti-inflammatory effects, potentially reducing inflammation in the body.

Hepatoprotective effects

Has the potential to protect the liver from toxins and oxidative stress.

Popularity in herbal supplements

Widely used in herbal supplements and traditional medicine for liver health.

Anticancer potential

Investigated for its potential anticancer properties.

Anti-diabetic properties

Studied for its possible effects on managing or preventing diabetes.

Treatment for alcohol-related liver diseases

Being researched as a potential treatment for alcohol-related liver diseases.

Treatment for viral hepatitis

Explored as a possible treatment for viral hepatitis.
These properties highlight the various potential health benefits and applications of silybin, making it a compound of interest in the fields of herbal medicine, pharmaceuticals, and nutraceuticals.

Upstream product

• 107-86-8 3,3-dimethyl acrylaldehyde 
• 685844-45-5 (8R,9R)-5-Hydroxy-8,9-dimethyl-4-phenyl-8,9-dihydro-pyrano[2,3-f]chromene-2,10-dione 
• 680575-77-3 (8R,9S)-8,9-dihydro-8,9-dimethyl-5-methoxy-4-phenyl-2H,10H-benzo[1,2-b;5,6-b']dipyran-2,10-dione 
• 685844-48-8 (8R,9S)-5-Hydroxy-8,9-dimethyl-4-phenyl-8,9-dihydro-pyrano[2,3-f]chromene-2,10-dione 
• 1253976-72-5 (10R,11S,12R)-12-butoxy-11,12-dihydro-6,6,10,11-tetramethyl-4-phenyl-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one 
• 1253976-75-8 (10R,11S,12R)-12-ethoxy-11,12-dihydro-6,6,10,11-tetramethyl-4-phenyl-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one 
• 1255918-45-6 (2R,3R,4R)-3,4,10,10a-tetrahydro-4-hydroxy-2,3,10,10-tetramethyl-8-phenyl-2H,6H,9aH-cyclopropa[4,5]furo[2,3-f]pyrano[2,3-h]chromen-6-one 
• 17312-30-0 (10R,11R)-10,11-dihydro-4-phenyl-6,6,10,11-tetramethyl-2H,6H,12H-benzo[1,2-b;3,4-b';5,6-b'']tripyran-2,12-dione 

Relevant academic research and scientific papers

The Inophyllums, Novel Inhibitors of HIV-1 Reverse Transcriptase Isolated from the Malaysian Tree, Calophyllum inophyllum Linn

As part of a search for novel inhibitors of HIV-1 reverse transcriptase, the acetone extract of the giant African snail, Achatina fulica, was shown to be active. Fractionation of the extract yielded inophyllums A, B, C, and E and calophylloide (1a, 2a, 3a

New coumarins and triterpenes from Calophyllum inophyllum

Four new coumarins, 1-4, and two new triterpenes, 5 and 6, along with nine known compounds have been identified from the leaves of Calophyllum inophyllum on the basis of spectroscopic analyses and chemical methods. The structure of apetalolide (7), previously reported from C. apetalum, was revised by means of 2D-NMR, and the absolute configuration of the known compound inophyllum D (8) was established by a modified Mosher's method.

Concise Synthesis of Anti-HIV-1 Active (+)-Inophyllum B and (+)-Calanolide A by Application of (-)-Quinine-Catalyzed Intramolecular Oxo-Michael Addition

(-)-Quinine-catalyzed intramolecular oxo-Michael addition (IMA) of 7-hydroxy-5-methoxy-8-tigloylcoumarins was developed for the enantioselective construction of 2,3-dimethyl-4-chromanone systems in the context of the asymmetric synthesis of anti-HIV-1 act