152187-38-7 Usage
General Description
11,12-Dihydro-12α-hydroxy-6,6,10α,11α-tetramethyl-4-phenyl-2H,6H,10H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-2-one, also known as silybin or silibinin, is a flavonolignan compound derived from the milk thistle plant (Silybum marianum). It is known for its antioxidant and anti-inflammatory properties, as well as its potential hepatoprotective effects. Silybin has been studied for its potential to protect the liver from toxins and oxidative stress, making it a popular ingredient in herbal supplements and traditional medicine for liver health. It has also been investigated for its potential anticancer and anti-diabetic properties. Additionally, silybin is being researched for its potential as a treatment for alcohol-related liver diseases and viral hepatitis.
Check Digit Verification of cas no
The CAS Registry Mumber 152187-38-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,1,8 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 152187-38:
(8*1)+(7*5)+(6*2)+(5*1)+(4*8)+(3*7)+(2*3)+(1*8)=127
127 % 10 = 7
So 152187-38-7 is a valid CAS Registry Number.
152187-38-7Relevant articles and documents
The Inophyllums, Novel Inhibitors of HIV-1 Reverse Transcriptase Isolated from the Malaysian Tree, Calophyllum inophyllum Linn
Patil, Ashok D.,Freyer, Alan J.,Eggleston, Drake S.,Haltiwanger, R. Curtis,Bean, Mark F.,et al.
, p. 4131 - 4138 (1993)
As part of a search for novel inhibitors of HIV-1 reverse transcriptase, the acetone extract of the giant African snail, Achatina fulica, was shown to be active. Fractionation of the extract yielded inophyllums A, B, C, and E and calophylloide (1a, 2a, 3a
Concise Synthesis of Anti-HIV-1 Active (+)-Inophyllum B and (+)-Calanolide A by Application of (-)-Quinine-Catalyzed Intramolecular Oxo-Michael Addition
Sekino, Etsuko,Kumamoto, Takuya,Tanaka, Tomohiro,Ikeda, Tomoko,Ishikawa, Tsutomu
, p. 2760 - 2767 (2007/10/03)
(-)-Quinine-catalyzed intramolecular oxo-Michael addition (IMA) of 7-hydroxy-5-methoxy-8-tigloylcoumarins was developed for the enantioselective construction of 2,3-dimethyl-4-chromanone systems in the context of the asymmetric synthesis of anti-HIV-1 act