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Usage

Uses

Used in Insect Repellent Industry:
DEET is used as an active ingredient in insect repellents for its proven effectiveness in deterring and repelling mosquitoes and other biting insects. It provides a protective barrier against insect bites, reducing the risk of insect-borne diseases such as malaria, dengue fever, and Zika virus.
Used in Pesticide Production:
In the agricultural sector, DEET is employed as a component in the formulation of various pesticides. Its insecticidal properties contribute to controlling and managing pest populations, thereby protecting crops and ensuring food security.
Used in Lubricant Industry:
DEET is utilized in the production of lubricants, where it serves to reduce friction and wear between moving parts. Its incorporation into lubricants enhances their performance, leading to improved efficiency and longevity of machinery and equipment.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, DEET is used in the development of various medications and treatments. Its diverse chemical properties make it a valuable component in the formulation of drugs for different therapeutic applications.
Used in Plasticizer Production:
DEET is used in the production of plasticizers, which are additives incorporated into plastics to improve their flexibility, durability, and resistance to heat. This enhances the performance and utility of plastic materials in a wide range of consumer and industrial products.

Upstream product

• 16369-21-4 N-(2-hydroxyethyl)-N-propylamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1434047-87-6 tert-butyl 2-(5-(phenylethynyl)pyridin-3-yloxy)ethyl(propyl)carbamate 
• 1434047-73-0 N-(2-(5-(phenylethynyl)pyridin-3-yloxy)ethyl)propan-1-amine 
• 1434047-86-5 tert-butyl 2-(5-bromopyridin-3-yloxy)ethyl(propyl)carbamate 
• 850724-05-9 3-{4-[2-(propyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester 
• 850724-03-7 3-[4-(2-propylamino-ethoxy)-phenyl]-propionic acid methyl ester 
• 850724-00-4 3-{4-[2-(tert-butoxycarbonyl-propyl-amino)-ethoxy]-phenyl}-propionic acid methyl ester 

Relevant academic research and scientific papers

Structure-property relationships of antibacterial amphiphilic polymers derived from 2-aminoethyl acrylate

The findings from the investigation of an ensemble of amphiphilic polymers derived from 2-aminoethyl acrylate establish significant effects of variation in the topographical position of the cationic center and hydrophobic segments on their biological activities. For example, the isomeric polymer pair of poly(6-aminohexylacrylate) and poly(2-(butylamino)ethyl acrylate) show striking differences in their biological activities, with the former having biological activities orders of magnitude higher. The trend of the activities of alkyl tails attached to the charge center shows an abrupt increase in biological activity at butyl length in the series of methyl to butyl tail. The distribution and interaction of the charge center in the chain domain is one of the main parameters in influencing polymer activities. Within the 2-aminoethyl acrylate system of homo- and copolymer, the homopolymer has its cationic centers closely distributed along the amphiphilic macromolecular chain with proximity to the backbone leading to rigid conformations not conducive to the attachment of the polymer to the cell surface. In copolymers, the incorporation of uncharged counits increases the distance between the cationic centers, resulting in significant reduction of charge repulsion and thus enhancing the flexibility of the chain conformation. This is conducive for polymer-cell association, leading to a remarkable surge in orders of magnitude of biological activity but with low selectivity against bacteria over red blood cells.

Design, synthesis, and biological activity of novel PPARγ ligands based on rosiglitazone and 15d-PGJ2

To develop novel PPARγ ligands, we synthesized thirteen 3-{4-(2-aminoethoxy)phenyl}propanoic acid derivatives, which are designed based on the structures of rosiglitazone and 15d-PGJ2. Among these compounds, compound 9 was found to be as potent as rosiglitazone in a binding assay and a preadipocyte differentiation test. Molecular modeling suggested that the nonyl group of 9 interacted with hydrophobic amino acid residues constructing the hydrophobic region of PPARγ protein where the alkyl chain of 15d-PGJ2 is expected to be located.