1522-77-6Relevant articles and documents
Hansch analysis of veratric acid derivatives as antimicrobial agents
Narasimhan, Balasubramanian,Ohlan, Sucheta,Ohlan, Ruchita,Judge, Vikramjeet,Narang, Rakesh
experimental part, p. 689 - 700 (2009/09/08)
The synthesis, characterization and antimicrobial evaluation of a new series of veratric acid derivatives are presented. Preliminary in vitro antimicrobial activity of the title compounds was assessed against a panel of microorganisms including Gram-positive and Gram-negative bacteria and fungi. Some of the veratric acid derivatives exhibited significant in vitro antimicrobial activity. QSAR investigation applied to find a correlation between different physicochemical parameters of the veratric acid derivatives and their antimicrobial activity indicated the importance of topological parameters in describing the antimicrobial activity.