1522-89-0Relevant articles and documents
Precisely tunable engineering of sub-30 nm monodisperse oligonucleotide nanoparticles
Sizovs, Antons,Song, Xianzhou,Waxham, M. Neal,Jia, Yilong,Feng, Fude,Chen, Jianwei,Wicker, Amanda C.,Xu, Jianming,Yu, Yan,Wang, Jin
, p. 234 - 240 (2014)
Advancement of RNAi therapies is mainly hindered by the development of efficient delivery vehicles. The ability to create small size (30 nm) oligonucleotide nanoparticles is essential for many aspects of the delivery process but is often overlooked. In t
Synthesis and antibacterial activity of new tetrakisquaternary ammonium compounds based on pentaerythritol and 3-hydroxypyridine
Vereshchagin,Minaeva,Egorov
, p. 545 - 548 (2021)
Tetrakisquaternary ammonium compounds based on pentaerythritol were synthesized for the first time. Bacteriostatic effect of the obtained compounds was evaluated towards opportunistic gram-positive Methicillin-resistant Staphylococcus aureus (strain ATCC
(S) or (R)-diphenyl-pyrrolidine methanol immobilized by pentaerythritol and its preparation method and application
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Paragraph 0012, (2018/03/28)
The invention discloses a (S/R)-diphenyl-pyrrolidine methanol immobilized by pentaerythritol and its preparation method and application. The (S/R)-diphenyl-pyrrolidine methanol is shown as Formula (I). The preparation of the catalyst includes steps of reacting pentaerythritol with paratoluensulfonyl chloride to obtain pentaerythritol sulphonate; reacting with sodium azide to obtain pentaerythritecompound; reacting (S/R)-N-Cbz-4-hydroxyproline methyl ester with propargyl bromide to obtain (S/R)-N-Cbz-4-acetylene methoxy proline methyl ester; then reacting with chlorophenylmagnesium to obtain (S/R)-diphenyl-pyrrolidine methanol immobilized by pentaerythritol. The (S/R)-diphenyl-pyrrolidine methanol immobilized by pentaerythritol can be applied to the reaction of asymmetrical transformationand generation of prochiral phenyl ketones to be (R/S)- secondary alcohol; the catalyst can be recycled.
Four (4-triazole phenyl) qtr fifth heavenly stem four ether preparation method and application
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Paragraph 0031, (2017/03/14)
A tetra(4-triazolephenyl) pentaerythritol ether single crystal and a preparing method thereof are disclosed. The tetra(4-triazolephenyl) pentaerythritol ether single crystal is prepared by adopting a "one-pot" method, namely by heating p-bromophenyl penta