1522157-83-0Relevant academic research and scientific papers
Electrophilic ipso-iodocyclization of N-benzyl-N-(1-naphthyl)propiolamides: Synthesis of complex polycyclic lactams
Wang, Li-Jing,Zhu, Hai-Tao,Qiu, Yi-Feng,Liu, Xue-Yuan,Liang, Yong-Min
, p. 643 - 650 (2014)
An intramolecular electrophilic ipso-iodocyclization of N-benzyl-N-(1-naphthyl)propiolamides combined with the Friedel-Crafts-type reaction for the synthesis of complex polycyclic lactams is reported. The resulting iodinated cyclization product can provide a very useful handle for further structural manipulation. The Royal Society of Chemistry.
