15228-71-4 Usage
Uses
Used in Antineoplastic Applications:
Vinrosidine is used as an antineoplastic agent for its potential in treating various types of cancer. It is particularly effective in targeting and inhibiting the growth of cancer cells, making it a valuable component in cancer treatment regimens.
Used in Pharmaceutical Industry:
Vinrosidine is used as an active pharmaceutical ingredient for the development of cancer therapeutics. Its unique structure and antineoplastic properties make it a promising candidate for the creation of new drugs and treatment options for cancer patients.
Used in Research and Development:
Vinrosidine is utilized as a key compound in the research and development of novel cancer treatments. Its structural properties and antineoplastic activity provide valuable insights for scientists and researchers working on the development of new cancer therapies.
References
Svoboda., Lloydia, 24, 173 (1961)
Structure:
Neuss, Huckstep, Cone., Tetrahedron Lett., 811 (1967)
Check Digit Verification of cas no
The CAS Registry Mumber 15228-71-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,2 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15228-71:
(7*1)+(6*5)+(5*2)+(4*2)+(3*8)+(2*7)+(1*1)=94
94 % 10 = 4
So 15228-71-4 is a valid CAS Registry Number.
InChI:InChI=1/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37+,38-,39-,42-,43-,44-,45+,46+/m1/s1
15228-71-4Relevant academic research and scientific papers
Preparation of leurosidine and novel leurosidine 4'-ethers and esters
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, (2008/06/13)
Vincaleukoblastine (VLB, vinblastine) is converted to leurosidine, its 4' epimer, by reaction with thionyl chloride to form a bis-sulfite ester followed by treatment of the bis-sulfite ester with silver perchlorate. The bis-sulfite ester is covertible to novel 4' ethers by treatment with a lower alkanol or 4' esters of leurosidine perchlorate with acetic anhydride.
