1522975-24-1

Upstream product

• 1522974-99-7 5-(4-nitrobenzyloxy)-1,4,4a,9a-tetrahydro-1,4-ethanoanthracene-9,10-dione 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 145212-76-6 endo-1,4-Ethano-5-hydroxy-1,4,4a,9a-tetrahydro-9,10-anthraquinone 

Relevant academic research and scientific papers

A small molecule for controlled generation of reactive oxygen species (ROS)

Due to the short half-life of reactive oxygen species (ROS) such as a superoxide radical, controlled and localized generation of ROS is challenging. Here, we report a rationally designed small-molecule 1c that generates ROS only when triggered by a bacterial enzyme. We provide evidence for 1c predictably enhancing the intracellular superoxide radical in a model bacterium. Spatiotemporal control over ROS generation offered by 1c should help better understand stress responses in bacteria to increased ROS.