152299-13-3

Upstream product

• 159497-65-1 N,N-dibenzylasparaginic acid dibenzyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 137428-32-1 (2S)-2-[bis(phenylmethyl)amino]-1,4-butanediol 

Downstream Products

• 152299-02-0 (S)-1-<2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl>-N-phthalimide 
• 152298-95-8 (R)-2-<1-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl>-N-phthalimide 
• 137604-26-3 (S)-4-amino-3-(N,N-dibenzylamino)-1-butanol 
• 152299-03-1 (R)-3-(N,N-dibenzylamino)-5-<(tert-butyldimethylsilyl)oxy>pentanenitrile 
• 152299-01-9 (R)-2-<(N,N-dibenzylamino)methyl>-4-<(tert-butyldimethylsilyl)oxy>butanenitrile 
• 159497-82-2 (S)-2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>-1-butylamine 
• 159497-86-6 (R)-1-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>-2-butylamine 
• 159497-55-9 (S)-1-<2-(N,N-dibenzylamino)-4-hydroxybutyl>-N-pyrrolidine 
• 159497-90-2 (S)-1-<1-<2-(N,N-dibenzylamino)-4-hydroxybutyl>>pyrrolidin-3-one 
• 159497-69-5 (S)-1-<1-<2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl>>pyrrolidine 
• 159497-89-9 (S)-1-<1-<2-(N,N-dibenzylamino)-4-<(tert-butyldimethylsilyl)oxy>butyl>>pyrrolidin-3-one 
• 159497-96-8 tert-butyl (S)-1-<1-<2-(N,N-dibenzylamino)-4-hydroxybutyl>>-3-hydroxypyrrole-2-carboxylate 

Relevant academic research and scientific papers

Monocarbamates, derived from (S)-2-(dibenzylamino)butane-1,4-diol, and the influence of the second O-protecting group on the regioselectivity of deprotonation - Application to the synthesis of the boletus toxin (2S,4S)-γ-hydroxy-norvaline

Differentially protected 1-O- and 4-O-monocarbamates, derived from (S)-2-(dibenzylamino)butane-1,4-diol are prepared and investigated with respect to their capability of being deprotonated and forming the corresponding lithium carbanions. In the 1-O-trity

Enantiomerically pure amino alcohols and diamino alcohols from L-aspartic acid. Application to the synthesis of epi- and diepislaframine

Starting from natural aspartic acid (6) a practical method for the synthesis of enantiomerically pure 3-amino alcohols 8 including 3,4-diamino derivatives is described. After perbenzylation of 6 and reduction of both carboxylates, position 4 of the result

PRACTICAL EPC SYNTHESIS OF 1,2- AND 1,3-AMINO ALCOHOLS

An efficient synthesis of enantiomerically pure 1,2- and 1,3-amino alcohols (4,10) through the key intermediates 2 and 8a,b, obtained from L-aspartic acid, is reported.Using 4d as an example it is shown that the products can serve as percursors for unusual amino aldehydes and nonproteinogenic amino acids.