152390-99-3

Upstream product

• 81028-12-8 (4S,5R)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-5-carboxaldehyde 
• 152390-97-1 N-Benzyl-N-[(S)-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-furan-2-yl-methyl]-hydroxylamine 
• 152390-96-0 (Z)-N-(4-O-benzyl-1-deoxy-2,3-O-isopropylidene-L-ylidene)benzylamine-N-oxide 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 19396-05-5 5-O-carbamoylpolyoxamic acid 

Relevant academic research and scientific papers

Applications of Sugar Nitrones in Synthesis: The Total Synthesis of (+)-Polyoxin J

A convergent synthesis of the peptidyl nucleoside antibiotic (inhibitor of chitin biosynthesis) polyoxin J (2) by coupling of 5-O-carbamoyl polyoxamic acid (3) and thymine polyoxin C (4) is described. These compounds were prepared by chain elongation and

Addition of 2-lithiofuran to chiral α-alkoxy nitrones; a stereoselective approach to α-epimeric β-alkoxy-α-amino acids

The addition of 2-lithiofuran (1) to the N-benzyl nitrones 2a-d, derived from chiral α-alkoxy aldehydes, affords β-alkoxy-α-hydroxyamino-2-alkylfurans in good yields and with syn selectivity. Conversely, the reaction with the same nitrones precomplexed wi

Stereocontrol by diethylaluminum chloride in the addition of 2-lithiofuran and N-methyl-2-lithioimidazole to αalkoxy nitrones. Total synthesis of 5-O-carbamoylpolyoxamic acid

The addition of the title metalated heterocycles 1 to the nitrone 2 derived from D-glyceraldehyde acetonide leads to the corresponding syn-adducts as major products (ds 88-96 %) while the reaction in the presence of Et2AlCl leads to anti isomer