152398-99-7

Basic information

• Product Name: 1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-
• Synonyms: 1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-
• CAS NO: 152398-99-7
• Molecular Formula: C7H17NO3
• Molecular Weight: 163.21
• Mol File: 152398-99-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-(152398-99-7)
• EPA Substance Registry System: 1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-(152398-99-7)

Safety Data

• Hazardous Substances Data: 152398-99-7(Hazardous Substances Data)

Usage

General Description

1,2-Propanediol, 3-(2-amino-1-methylpropoxy)-, also known as ziconotide, is a synthetic peptide derivative that is primarily used as a medication for the management of severe chronic pain. It works by blocking the N-type calcium channels in the central nervous system, which in turn inhibits the release of neurotransmitters involved in pain signaling. Ziconotide is administered intrathecally, meaning it is delivered directly to the cerebrospinal fluid surrounding the spinal cord, making it effective at lower doses and reducing the risk of systemic side effects. However, it may cause side effects such as headache, dizziness, and confusion, and should not be used in individuals with a history of psychosis or psychotic disorders. Overall, ziconotide is a valuable tool in the treatment of severe chronic pain when other medications have proven ineffective.