152430-95-0

Basic information

• Product Name: 10-(3,5-Dimethoxy-phenyl)-decan-1-ol
• Synonyms: 10-(3,5-Dimethoxy-phenyl)-decan-1-ol
• CAS NO: 152430-95-0
• Molecular Weight: 294.434
• Mol File: 152430-95-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 10-(3,5-Dimethoxy-phenyl)-decan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 10-(3,5-Dimethoxy-phenyl)-decan-1-ol(152430-95-0)
• EPA Substance Registry System: 10-(3,5-Dimethoxy-phenyl)-decan-1-ol(152430-95-0)

Safety Data

• Hazardous Substances Data: 152430-95-0(Hazardous Substances Data)

Upstream product

• 104876-10-0 9-(phenylmethoxy)nonan-1-ol 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 157730-78-4 9-benzyloxy-1-nonanal 
• 3937-56-2 1,9-Nonanediol 
• 148808-16-6 1,3-dimethoxy-5-<10-(2-tetrahydropyranyloxy)-1-decenyl>benzene 
• 70863-80-8 9-((tetrahydro-2H-pyran-2-yl)oxy)nonan-1-al 
• 67136-13-4 1-(tetrahydro-2-pyranyloxy)-9-decene 
• 148808-17-7 1,3-dimethoxy-5-<10-(2-tetrahydropyranyloxy)decanyl>benzene 
• 13019-22-2 9-Decen-1-ol 

Downstream Products

• 34809-61-5 1,3-dimethoxy-5-<(Z)-10'-pentadecenyl>benzene 
• 82380-21-0 maesanin 
• 87746-51-8 dimethoxymaesanin 
• 137786-94-8 belamcandol B 
• 137786-93-7 belamcandaphenol 
• 148808-18-8 2-Bromo-5-methoxy-3-((Z)-pentadec-10-enyl)-phenol 
• 97987-89-8 belamcandaquinone 
• 148808-21-3 1,4-dihydroxy-2-methoxy-6-<(Z)-10'-pentadecenyl>benzene 
• 148808-20-2 2-bromo-5-methoxy-3-<(Z)-10'-pentadecenyl>-1,4-benzoquinone 
• 144078-13-7 3-Methoxy-5-<(Z)-heptadec-10'-enyl>phenol 
• 56495-82-0 (Z)-2-(heptadec-10-en-1-yl)-6-methoxycyclohexa-2,5-diene-1,4-dione 
• 77285-25-7 (Z)-2-(heptadec-10-en-1-yl)-6-methoxybenzene-1,4-diol 
• 137786-97-1 10-(3,5-dimethoxyphenyl)decanal 

Relevant articles and documents

Identification of novel ROS inducers: Quinone derivatives tethered to long hydrocarbon chains

We performed the first synthesis of the 17-carbon chain-tethered quinone moiety 22 (SAN5201) of irisferin A, a natural product exhibiting anticancer activity, and its derivatives. We found that 22 is a potent ROS inducer and cytotoxic agent. Compound 25 (SAN7401), the hydroquinone form of 22, induced a significant release of intracellular ROS and apoptosis (EC50 = 1.3-2.6 μM) in cancer cell lines, including A549 and HCT-116. Compared with the activity of a well-known ROS inducer, piperlongumine, 22 and 25 showed stronger cytotoxicity and higher selectivity over noncancerous cells. Another hydroquinone tethering 12-carbon chain, 26 (SAN4601), generated reduced levels of ROS but showed more potent cytotoxicity (EC50 = 0.8-1.6 μM) in cancer cells, although it lacked selectivity over noncancerous cells, implying that the naturally occurring 17-carbon chain is also crucial for ROS production and a selective anticancer effect. Both 25 and 26 displayed strong, equipotent activities against vemurafenib-resistant SK-Mel2 melanoma cells and p53-deficient H1299 lung cancer cells as well, demonstrating their broad therapeutic potential as anticancer agents.