152449-64-4 Usage
General Description
(2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one, also known as Cilastatin, is a potent antibiotic drug commonly used in combination with Imipenem to treat severe infections. The chemical structure of Cilastatin includes a thiazolidine-4-one ring with an imino group, a chlorophenyl group, and a phenylmethylidene group. (2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one acts as a renal dehydropeptidase inhibitor, allowing Imipenem to remain active in the body for longer periods, thereby enhancing its effectiveness in combatting bacterial infections. Cilastatin is considered an essential medication in the treatment of a variety of infections, particularly those caused by multi-drug resistant bacteria.
Check Digit Verification of cas no
The CAS Registry Mumber 152449-64-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,4,4 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 152449-64:
(8*1)+(7*5)+(6*2)+(5*4)+(4*4)+(3*9)+(2*6)+(1*4)=134
134 % 10 = 4
So 152449-64-4 is a valid CAS Registry Number.
152449-64-4Relevant articles and documents
Thiazolidinone congeners as central nervous system active agents
Tripathi,Verma,Gujrati,Palit,Shanker
, p. 632 - 635 (2007/10/02)
3-(Benzylidene amino)-2-imino-4-thiazolidinones (IIa-c) synthesized by cyclization of substituted thiosemicarbazones (Ia-c) were converted into 2-amino-3-(substited benzylamino)-4-thiazolidinones (IIIa-c), 2-imino-3-(α-aryl azo benzylidene) amino-4-thiazo
