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152460-07-6

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152460-07-6 Usage

General Description

The chemical Guanidine, (2-methyl-5-nitrophenyl), also referred to as Phenylguanidine, is an organic compound which includes a guanidine functional group attached to a 2-methyl-5-nitrophenyl residue. As the name suggests, this molecule is characterized by the presence of nitro and methyl groups on a phenyl ring, making it part of the nitro compounds and aromatic compounds chemical families. Its properties and reactions are dictated by these functional groups. Commonly, it can be used in research as a reagent or precursor in the synthesis of more complex molecules. As with many chemicals, it should be carefully handled and stored, as it may pose health hazards upon exposure. Specific information regarding its physical and chemical properties, hazards, and safe handling procedures can be found on its Material Safety Data Sheet (MSDS).

Check Digit Verification of cas no

The CAS Registry Mumber 152460-07-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,4,6 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 152460-07:
(8*1)+(7*5)+(6*2)+(5*4)+(4*6)+(3*0)+(2*0)+(1*7)=106
106 % 10 = 6
So 152460-07-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N4O2/c1-5-2-3-6(12(13)14)4-7(5)11-8(9)10/h2-4H,1H3,(H4,9,10,11)

152460-07-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-methyl-5-nitrophenyl) nitrate

1.2 Other means of identification

Product number -
Other names Guanidine,(2-methyl-5-nitrophenyl)-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152460-07-6 SDS

152460-07-6Relevant articles and documents

Preparation method of 2-methyl-5-nitrophenyl guanidine

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Paragraph 0041-0043, (2021/11/14)

The invention relates to a preparation method of 2-methyl-5-nitrophenyl guanidine, and belongs to the technical field of synthesis of drug intermediates. In order to solve the problems of high reaction corrosivity and low yield in the prior art, the invention provides a preparation method of 2-methyl-5-nitrophenyl guanidine, which comprises the following step: in the presence of an acid-binding agent, carrying out a condensation reaction on 2-chloro-4-nitrotoluene and guanidine hydrochloride in an alcohol solvent to obtain the corresponding product 2-methyl-5-nitrophenyl guanidine. According to the method, high efficiency and conversion rate can be achieved, the product yield reaches 90% or above, and the purity reaches 99% or above. The reaction conditions are mild, the operation is easier, the cost is relatively low, and the industrial production is more facilitated.

COMPOSITIONS AND METHODS FOR INHIBITING KINASES

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Page/Page column 33-34, (2016/11/14)

The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject.

PROCESSES FOR THE PREPARATION OF IMATINIB BASE AND INTERMEDIATES THEREOF

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Page/Page column 21, (2013/03/26)

The invention relates to an improved process for the preparation of highly pure imatinib base (99.99% HPLC purity) of formula (I) and the pharmaceutically acceptable acid addition salts thereof. This invention also relates to processes for the preparation of the intermediates in the synthesis of imatinib base.

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