152481-90-8

Basic information

• Product Name: Acetic acid, dichloro-, (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester
• CAS NO: 152481-90-8
• Molecular Formula: C18H24Cl2O2
• Molecular Weight: 343.293
• Mol File: 152481-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, dichloro-, (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, dichloro-, (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester(152481-90-8)
• EPA Substance Registry System: Acetic acid, dichloro-, (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl ester(152481-90-8)

Safety Data

• Hazardous Substances Data: 152481-90-8(Hazardous Substances Data)

Upstream product

• 79-36-7 dichloroacethyl chloride 
• 65253-04-5 (-)-8-phenylmenthol 

Downstream Products

• 71804-27-8 (1R,2S,5R)-(+)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl chloroacetate 

Relevant articles and documents

SYNTHESIS OF THIOALDEHYDES HAVING OPTICALLY ACTIVE ALKOXY MOIETY AND THEIR ASYMMETRIC HETERO DIELS-ALDER REACTION

Optically active α-alkoxycarbonylthioaldehydes (2a-g) were prepared using 8-arylmenthols as chiral auxiliaries.Their asymmetric hetero Diels-Alder reactions with cyclopentadiene gave the endo cycloadducts (3 and 4) and exo cycloadducts (5 and 6) with moderate diastereomeric excesses.However, the major endo cycloadducts (3b-g) were isolated in optically pure form.This is the first chiral synthesis of 2-thiabicyclohept-5-ene ring system.The absolute configuration of the cyclic carbonate (12), which was prepared from the major endo cycloadduct (3c) via the epimerization, or the minor exo compound (6c), was determined as 1R by X-ray analysis.The cycloadduct (3c) was trasformed to a potential intermediate (14) for the synthesis of carbocyclic homonucleosides.