15249-31-7

Basic information

• Product Name: 2-Propynamide, N-methyl-N-phenyl-
• Synonyms: N-Methylpropiolanilide;N-Methyl-propiolanilid;2-Propynamide,N-methyl-N-phenyl;N-methyl-N-phenylpropiolamide
• CAS NO: 15249-31-7
• Molecular Formula: C10H9NO
• Molecular Weight: 159.188
• Mol File: 15249-31-7.mol
• Article Data: 14

Chemical Properties

• Melting Point: 78-79 °C(Solv: isopropyl ether (108-20-3))
• Boiling Point: 240.4±23.0 °C(Predicted)
• Density: 1.126±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Propynamide, N-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynamide, N-methyl-N-phenyl-(15249-31-7)
• EPA Substance Registry System: 2-Propynamide, N-methyl-N-phenyl-(15249-31-7)

Safety Data

• Hazardous Substances Data: 15249-31-7(Hazardous Substances Data)

Upstream product

• 4672-74-6 propiolic acid anhydride 
• 100-61-8 N-methylaniline 
• 471-25-0 Propiolic acid 
• 615-43-0 2-iodophenylamine 
• 154867-50-2 N-(2-iodophenyl)propiolamide 
• 906799-07-3 N-(2-iodophenyl)-N-methylpropiolamide 
• 5683-31-8 3-(trimethylsilyl)prop-2-ynoic acid 
• 7341-97-1 N-phenyl propynamide 
• 74-88-4 methyl iodide 

Downstream Products

• 14376-87-5 trans-3-Dibenzylamino-1-(methyl-phenylamino)-prop-2-en-1-on 
• 86576-69-4 (E)-N-methyl-3-morpholino-N-phenylacrylamide 
• 1088706-81-3 (Z)-3-(5-amino-3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazol-4-ylthio)-N-methyl-N-phenylacrylamide 
• 94298-51-8 N-methyl-N,3-diphenylprop-2-ynamide 
• 1343395-39-0 3-iodo-N-methyl-N-phenylpropiolamide 
• 84088-88-0 methyl 3-(N-methyl-N-phenylamino)-3-oxopropanoate 
• 59050-15-6 ethyl 3-(N-methyl-N-phenylamino)-3-oxopropionate 
• 1319767-67-3 allyl 3-(methyl(phenyl)amino)-3-oxopropanoate 
• 1431884-92-2 benzyl 3-(methyl(phenyl)amino)-3-oxopropanoate 
• 1410941-38-6 methyl 2-methyl-3-(methyl(phenyl)amino)-3-oxopropanoate 
• 1013905-87-7 N-methyl-N-phenyl-3-(4-methylphenyl)propargylamide 
• 1238625-75-6 3-(4-fluorophenyl)-N-methyl-N-phenylprop-2-ynamide 
• 1343395-48-1 3-(4-chlorophenyl)-N-methyl-N-phenylprop-2-ynamide 

Relevant articles and documents

New alkyne esters and alkyneamide plant antibacterial agents

The present invention relates to a class of propyne esters and propyneamide compounds and synthetic methods thereof, and drugs containing the compound and applications thereof. The two types of compounds have efficient and broad-spectrum inhibitory activity for more than ten kinds of plant pathogenic fungi, and at the same time have the characteristics of simple structure, easy large-scale preparation and high safety of animals and plants, and can be used as active ingredients for the development of new plant antibacterial agents with high efficiency and low toxicity.

Metal-Free Synthesis of Selenodihydronaphthalenes by Selenoxide-Mediated Electrophilic Cyclization of Alkynes

A transition-metal-free, selenium mediated electrophilic cyclization reaction was realized through a one-pot procedure between simple alkynes and triflic anhydride-activated selenoxides to give selenium containing dihydronaphthalene products. This method gave good to very high yields for all products, including selenium-substituted phenanthrene, dihydroquinoline, 2H-chromene, and coumarin, which can be further transformed to other functionalized compounds.

Palladium-Catalyzed Regio- and Stereoselective Coupling-Addition of Propiolates with Arylsulfonyl Hydrazides: A Pattern for Difunctionalization of Alkynes

A new pattern for difunctionalization of alkynes via a palladium-catalyzed regio- and stereoselective coupling-addition of propiolates with arylsulfonyl hydrazides is disclosed. The approach enables the synthesis of various highly functionalized (E)-vinylsulfones in satisfactory yields. Arylsulfonyl hydrazides act as both aryl and sulfonyl sources via selective cleavage of Ar(C)-S and S-N bonds, which are simultaneously incorporated onto the terminal carbon atom of an alkyne molecule.