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152502-85-7

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  • 2(1H)-Pyrimidinone,4-amino-1-[2-deoxy-2-(fluoromethyl)-b-D-arabinofuranosyl]-

    Cas No: 152502-85-7

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152502-85-7 Usage

General Description

1-(2-deoxy-2-C-fluoromethylarabinofuranosyl)cytosine, also known as F-ara-EdU, is a synthetic nucleoside analogue that is a potential anticancer agent. It is a nucleoside analog of cytidine with a fluorine substitution at the C2' position of the sugar moiety. This modification increases the molecule's resistance to degradation by glycosylases, making it an effective DNA replication inhibitor. F-ara-EdU has shown promise in preclinical studies for the treatment of various cancers, particularly solid tumors, and its unique mechanism of action makes it a potential candidate for combination therapies with other chemotherapeutic agents. Additionally, its use as a probe for the detection of DNA synthesis and replication in research and diagnostic applications has been investigated.

Check Digit Verification of cas no

The CAS Registry Mumber 152502-85-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,5,0 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 152502-85:
(8*1)+(7*5)+(6*2)+(5*5)+(4*0)+(3*2)+(2*8)+(1*5)=107
107 % 10 = 7
So 152502-85-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14FN3O4/c11-3-5-8(16)6(4-15)18-9(5)14-2-1-7(12)13-10(14)17/h1-2,5-6,8-9,15-16H,3-4H2,(H2,12,13,17)/t5-,6+,8-,9?/m0/s1

152502-85-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-1-[(3S,4S,5R)-3-(fluoromethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 1-(2-Deoxy-2-C-fluoromethylarabinofuranosyl)cytosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:152502-85-7 SDS

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