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1-(2-deoxy-2-C-fluoromethylarabinofuranosyl)cytosine, also known as F-ara-EdU, is a synthetic nucleoside analogue derived from cytidine with a fluorine substitution at the C2' position of the sugar moiety. This modification enhances the molecule's resistance to degradation by glycosylases, making it an effective DNA replication inhibitor. F-ara-EdU has demonstrated potential as an anticancer agent, particularly against solid tumors, and its unique mechanism of action positions it as a candidate for combination therapies with other chemotherapeutic agents. Furthermore, its application as a probe for detecting DNA synthesis and replication in research and diagnostic settings is being explored.

152502-85-7

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152502-85-7 Usage

Uses

Used in Anticancer Applications:
1-(2-deoxy-2-C-fluoromethylarabinofuranosyl)cytosine is used as an anticancer agent for its potential to treat various solid tumors. Its unique mechanism of action, which involves inhibiting DNA replication, makes it a promising candidate for combination therapies with other chemotherapeutic drugs, potentially enhancing the overall treatment efficacy.
Used in Research and Diagnostic Applications:
In the field of research and diagnostics, 1-(2-deoxy-2-C-fluoromethylarabinofuranosyl)cytosine is used as a probe for detecting DNA synthesis and replication. Its ability to inhibit DNA replication and its resistance to degradation make it a valuable tool for studying cellular processes and developing diagnostic tests for various conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 152502-85-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,5,0 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 152502-85:
(8*1)+(7*5)+(6*2)+(5*5)+(4*0)+(3*2)+(2*8)+(1*5)=107
107 % 10 = 7
So 152502-85-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14FN3O4/c11-3-5-8(16)6(4-15)18-9(5)14-2-1-7(12)13-10(14)17/h1-2,5-6,8-9,15-16H,3-4H2,(H2,12,13,17)/t5-,6+,8-,9?/m0/s1

152502-85-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-1-[(3S,4S,5R)-3-(fluoromethyl)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 1-(2-Deoxy-2-C-fluoromethylarabinofuranosyl)cytosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152502-85-7 SDS

152502-85-7Upstream product

152502-85-7Downstream Products

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