152529-40-3Relevant academic research and scientific papers
Enantioselective Michael Additions of Grignard Reagents to Cinnamamides deriving from N-Fluoroalkyl (R)-(-)-2-Aminobutan-1-ol. Determination of Diastereomeric Excess by means of 19F NMR
Touet, Joel,Grumelec, Christelle Le,Huet, Francois,Brown, Eric
, p. 1469 - 1472 (2007/10/02)
N-Alkylation of (R)-(-)-2-aminobutan-1-ol 1 (a readily available reagent) with ortho-fluorobenzyl chloride, followed by reaction with cinnamoyl chloride, afforded the cinnamamide (R)-(+)-6.Michael addition of n-alkyl magnesium halides to the latter gave t
