152646-58-7Relevant academic research and scientific papers
A novel mimic of the sialyl Lewis x determinant
Allanson,Davidson,Martin
, p. 3945 - 3948 (1993)
The syntheses of two novel disaccharides are described which block the interaction of the lectin domain of E-selectin with its glycosylated ligands on neutrophils.
The Synthesis of Novel Mimics of the Sialyl Lewis X Determinant
Allanson, Nigel M.,Davidson, Alan H.,Floyd, Christopher D.,Martin, Fionna M.
, p. 2061 - 2076 (2007/10/02)
Disaccharide mimics of the sialyl Lewis X (sLex) ligands have been prepared as potential antagonists of binding to the lectin domains of the E-selectin adhesion molecule.Versatile derivatives of sialic acid provide an entry to a series of simpl
