152696-50-9

Upstream product

• 3970-21-6 2-Methoxyethoxymethyl chloride 
• 153061-95-1 C₁₈H₂₈O₅ 
• 152696-49-6 (4aR,8aR)-2,3,4a,5,6,7,8,8a-Octahydro-1H-4,9-dioxa-benzo[f]azulen-10-one 
• 1072-86-2 (1R,2R)-trans-1,2-cyclohexanediol 
• 178232-52-5 (1S,2R)-2-[(E)-2-Phenyl-1-((R)-toluene-4-sulfinylmethyl)-vinyloxy]-cyclohexanol 
• 178159-34-7 (1S,2R)-2-[(E)-1-Benzyl-2-((R)-toluene-4-sulfinyl)-vinyloxy]-cyclohexanol 
• 178159-36-9 1-{(R)-(E)-2-[(1R,2S)-2-(2-Methoxy-ethoxymethoxy)-cyclohexyloxy]-3-phenyl-prop-2-ene-1-sulfinyl}-4-methyl-benzene 
• 178159-37-0 1-{(R)-(E)-2-[(1R,2S)-2-(2-Methoxy-ethoxymethoxy)-cyclohexyloxy]-3-phenyl-prop-1-ene-1-sulfinyl}-4-methyl-benzene 

Relevant academic research and scientific papers

Novel asymmetric desymmetrization of meso-1,2-diols via diastereoselective β-elimination of chiral α-arylsulfinyl acetals

Enantioselective desymmetrization of meso-1,2-diols was accomplished via diastereoselective C-O bond fission of acetals derived from various optically active β-ketosulfoxides with high diastereoselectivities. The substituent at the γ-position of the β-ketosulfoxide plays an important role in this cleavage.

Asymmetric Induction to meso-Cyclohexane-1,2-diol Based on Diastereoselective Elimination

Diastereoselective elimination of syn- and anti-1 under basic condition, and subsequent protection of the hydroxy group followed by acid hydrolysis of the enol ether function gave (1S,2R)-3 of 72percent ee.