152804-78-9

Basic information

• Product Name: 3-benzyloxy-5-bromo-2-ethyl-4H-pyran-4-one
• Synonyms: 3-benzyloxy-5-bromo-2-ethyl-4H-pyran-4-one
• CAS NO: 152804-78-9
• Molecular Weight: 309.159
• Mol File: 152804-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyloxy-5-bromo-2-ethyl-4H-pyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxy-5-bromo-2-ethyl-4H-pyran-4-one(152804-78-9)
• EPA Substance Registry System: 3-benzyloxy-5-bromo-2-ethyl-4H-pyran-4-one(152804-78-9)

Safety Data

• Hazardous Substances Data: 152804-78-9(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 95790-62-8 2-ethyl-3-hydroxy-5-bromo-4H-pyran-4-one 

Downstream Products

• 152804-81-4 3-Benzyloxy-2-ethyl-5-phenyl-pyran-4-one 

Relevant articles and documents

Synthesis Of 5-Aryl-3-Hydroxy-4H-Pyran-4-Ones

The palladium-catalyzed coupling reaction of 3-benzyloxy-5-bromo-2-methyl-4H-pyran-4-one (2b) with phenylboronic acid afforded efficiently 3-benzyloxy-2-methyl-5-phenyl-4H-pyran-4-one (3b-1), and the benzyloxy group of the resultant product was cleaved by hydrolysis with conc. hydrochloric acid in acetic acid to give 5-phenyl-3-hydroxy-2-methyl-4H-pyran-4-one (4b-1) in high yield.This method was applicable as a general method for synthesizing 5-aryl-3-hydroxy-4H-pyran-4-ones (4) from the 5-bromo-4H-pyran-4-ones (1).