152818-41-2

Upstream product

• 152818-34-3 1,2-dihydro-2,6,7-trimethyl-1-oxo-4-phenyl-3-isoquinolinecarboxylic acid 
• 159819-81-5 4-(2-fluorophenyl)-6,7-dimethylisocoumarin-3-carboxylic acid 

Relevant academic research and scientific papers

Condensed heterocyclic compounds, their production and use

Novel compound represented by the formula: STR1 such as 6-Chloro-N-(2,6-diethoxyphenyl)-4-(2-methylphenyl-2-oxo-2H-1-benzopyran-3-acetamide: STR2 or a salt thereof. The compound has an excellent activity of inhibiting ACAT, lowering the cholesterol in blood and inhibiting tachykinin receptor. The present invention also relates to the production and use of the disclosed compound.

Tachykinin receptor antagonists, isoquinolones and their production

Novel composition represented by the formula: STR1 wherein ring A and ring B each means a benzene ring which may be substituted; R means a hydrogen atom or an alkyl group which may be substituted; R1 means a hydrogen atom or an alkyl group which may be substituted; R2 means a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted, or R1 and R2, taken together with the adjacent nitrogen atom, jointly form a ring which may be substituted, or a pharmaceutically acceptable salt thereof which is a useful tachykinin receptor antagonist.