1528636-33-0 Usage
Uses
Used in Chemical Synthesis:
(2S,3R,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-3,4,5-tris-(trimethylsilyloxy)tetrahydro-2H-pyran-2-carbaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and functional groups.
Used in Material Science:
In the field of material science, (2S,3R,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-3,4,5-tris-(trimethylsilyloxy)tetrahydro-2H-pyran-2-carbaldehyde can be used as a precursor for the development of new polymers and materials with specific properties, such as improved thermal stability or enhanced chemical resistance.
Used in Biological Research:
(2S,3R,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-3,4,5-tris-(trimethylsilyloxy)tetrahydro-2H-pyran-2-carbaldehyde can be employed in biological research as a tool to study the interactions between small molecules and biological targets, such as enzymes or receptors, due to its diverse functional groups and stereochemistry.
Used in Analytical Chemistry:
(2S,3R,4S,5R,6S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxy-3,4,5-tris-(trimethylsilyloxy)tetrahydro-2H-pyran-2-carbaldehyde can also be utilized in analytical chemistry as a chiral derivatizing agent for the enantioselective analysis of various compounds, taking advantage of its multiple stereocenters and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 1528636-33-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,2,8,6,3 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1528636-33:
(9*1)+(8*5)+(7*2)+(6*8)+(5*6)+(4*3)+(3*6)+(2*3)+(1*3)=180
180 % 10 = 0
So 1528636-33-0 is a valid CAS Registry Number.
1528636-33-0Relevant academic research and scientific papers
AN EFFICIENT PROCESS FOR THE PREPARATION OF ERTUGLIFLOZIN L-PYROGLUTAMIC ACID AND INTERMEDIATES THEREOF
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, (2021/07/10)
The present invention relates to an efficient process for the preparation of Ertugliflozin L-pyroglutamic acid of formula (I) and intermediate thereof, in environment friendly conditions. The present invention further relates to a process for the preparation of substantially pure intermediate of formula (IV).
Development of an early-phase bulk enabling route to sodium-dependent glucose cotransporter 2 inhibitor ertugliflozin
Bernhardson, David,Brandt, Thomas A.,Hulford, Catherine A.,Lehner, Richard S.,Preston, Brian R.,Price, Kristin,Sagal, John F.,Pierre, Michael J. St.,Thompson, Peter H.,Thuma, Benjamin
, p. 57 - 65 (2014/05/20)
The development and optimization of a scalable synthesis of sodium-dependent glucose cotransporter 2 inhibitor, ertugliflozin, for the treatment of type-2 diabetes is described. Highlights of the chemistry are a concise, four-step synthesis of a structurally complex API from known intermediate 4 via persilylation-selective monodesilylation, primary alcohol oxidation, aldol-crossed-Cannizzaro reaction, and solid-phase acid-catalyzed bicyclic ketal formation. The final API was isolated as the Lpyroglutamic acid cocrystal.
