152874-20-9

Basic information

• Product Name: 3-<2-(Trimethylsilyl)ethinyl>-2-thiophencarbaldehyd
• Synonyms: 3-<2-(Trimethylsilyl)ethinyl>-2-thiophencarbaldehyd
• CAS NO: 152874-20-9
• Molecular Weight: 208.356
• Mol File: 152874-20-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 3-<2-(Trimethylsilyl)ethinyl>-2-thiophencarbaldehyd(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<2-(Trimethylsilyl)ethinyl>-2-thiophencarbaldehyd(152874-20-9)
• EPA Substance Registry System: 3-<2-(Trimethylsilyl)ethinyl>-2-thiophencarbaldehyd(152874-20-9)

Safety Data

• Hazardous Substances Data: 152874-20-9(Hazardous Substances Data)

Upstream product

• 930-96-1 3-bromo-2-thiophenecarboxaldehyde 
• 1066-54-2 trimethylsilylacetylene 

Relevant articles and documents

Palladium-catalyzed chemoselective aminomethylative cyclization and aromatizing allylic amination: Access to functionalized naphthalenes

A palladium-catalyzed chemoselective aminomethylative cyclization and aromatizing allylic amination of enyne-tethered allylic alcohols with aminals is described. Under the reaction conditions, the cationic vinyl allylpalladium species undergoes selective migratory insertion of alkenes rather than reductive elimination with nucleophiles. This strategy provides an efficient and unique approach to the construction of functionalized naphthalenes, which are important building blocks in synthetic organic chemistry. Mechanistic studies have revealed that the selective sequential migratory insertion of enyne and alkene is crucial for the cyclization.

Opioid receptor agonists and application thereof

The invention discloses compounds and salts thereof that can be used as opioid receptor ligands, a preparation method of the compounds, compositions containing the compounds, and a use of the compounds as [mu] opioid receptor agonists; the compounds are used for treatment of [mu] opioid receptor-mediated related diseases, such as pains and pain-related disorders.

Synthesis of Fluorescent Azafluorenones and Derivatives via a Ruthenium-Catalyzed [2 + 2 + 2] Cycloaddition

An original and mild synthetic route for the preparation of novel azafluorenones and derivatives via a ruthenium-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides has been developed. This atom-economical catalytic process demonstrated remarkable regioselectivities to access fluorescent azafluorenone derivatives. The photophysical properties of azafluorenone derivatives have been evaluated, and photoluminescence phenomena at solid and liquid states have been highlighted.